Successful in utero intervention for bilateral renal agenesis

Jessica L Bienstock, Meredith L. Birsner, Fred Coleman, Nancy A Hueppchen

Research output: Contribution to journalArticle

Abstract

BACKGROUND: We report a case of bilateral renal agenesis treated with serial amnioinfusion in which the newborn survived the newborn period and was able to undergo peritoneal dialysis as a bridge to planned renal transplantation. CASE: A 34-year-old woman, gravida 1 para 0, presented at 23 1/7 weeks of gestation with a diagnosis of anhydramnios and bilateral renal agenesis. The patient underwent weekly serial amnioinfusion with the goal of improving fetal pulmonary development. At 28 weeks of gestation, the patient delivered a live newborn who required minimal respiratory support. The neonate is currently 9 months old and is undergoing daily peritoneal dialysis. CONCLUSION: Serial amnioinfusion appears to have mitigated the severe pulmonary compromise that has, in the past, led to the death of newborns with bilateral renal agenesis.

Original languageEnglish (US)
Pages (from-to)413-415
Number of pages3
JournalObstetrics and Gynecology
Volume124
Issue number2 PART2
DOIs
StatePublished - 2014

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Newborn Infant
Peritoneal Dialysis
Pregnancy
Lung
Fetal Development
Kidney Transplantation
Hereditary renal agenesis

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Successful in utero intervention for bilateral renal agenesis. / Bienstock, Jessica L; Birsner, Meredith L.; Coleman, Fred; Hueppchen, Nancy A.

In: Obstetrics and Gynecology, Vol. 124, No. 2 PART2, 2014, p. 413-415.

Research output: Contribution to journalArticle

Bienstock, Jessica L ; Birsner, Meredith L. ; Coleman, Fred ; Hueppchen, Nancy A. / Successful in utero intervention for bilateral renal agenesis. In: Obstetrics and Gynecology. 2014 ; Vol. 124, No. 2 PART2. pp. 413-415.
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