Successful Endobronchial Resection of Obstructive Inflammatory Myofibroblastic Airway Tumor with Anaplastic Lymphoma Kinase (ALK) Positivity

Brendan O'Brien, Carolyn Rosner, Alexander Spira, Sandeep J. Khandhar, Amit K. Mahajan

Research output: Contribution to journalArticle

Abstract

Inflammatory myofibroblastic tumors are rare neoplasms that are typically found in the lungs or retroperitoneum. Traditionally, complete surgical resection achieves a favorable prognosis if adequate margins are obtained. This report describes the effective endobronchial treatment of an inflammatory myofibroblastic tumors causing left mainstem airway obstruction without regional extension or distant metastases. Although surgical interventions such as sleeve resection or complete pneumonectomy may be effective therapeutic options for parenchymal tumors, endobronchial therapy, with an understanding of anaplastic lymphoma kinase status, may offer an equally effective lung-sparing treatment option.

Original languageEnglish (US)
Pages (from-to)160-162
Number of pages3
JournalClinical Pulmonary Medicine
Volume24
Issue number4
DOIs
StatePublished - Jan 1 2017
Externally publishedYes

Keywords

  • anaplastic lymphoma kinase
  • endobronchial resection
  • inflammatory myofibroblastic tumor
  • rigid bronchoscopy

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine

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