Subtyping: What It is and Its Role in Precision Medicine

Suchi Saria, Anna Goldenberg

Research output: Contribution to journalArticle

Abstract

Precision medicine is an emerging approach that considers variability in genes, environment, and lifestyle in order to better treat individuals. This article gives an overview of the diverse approaches to subtyping, from early accounts based on clinical practice to more recent approaches that focus on computationally derived subtypes based on molecular and electronic health record (EHR) data. This field is expansive and growing rapidly; the authors juxtapose approaches taken by different communities and highlight examples of significant open computational problems.

Original languageEnglish (US)
Article number7156005
Pages (from-to)70-75
Number of pages6
JournalIEEE Intelligent Systems
Volume30
Issue number4
DOIs
StatePublished - Jul 1 2015

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Keywords

  • disease subtyping
  • electronic health record
  • precision medicine
  • verotype

ASJC Scopus subject areas

  • Computer Networks and Communications
  • Artificial Intelligence

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