TY - JOUR
T1 - Subtyping schizophrenia
T2 - A comparison of positive/negative and system-specific approaches
AU - Lang, F. U.
AU - Walther, S.
AU - Stegmayer, K.
AU - Anderson-Schmidt, H.
AU - Schulze, T. G.
AU - Becker, T.
AU - Jäger, M.
PY - 2015/8/1
Y1 - 2015/8/1
N2 - Background Schizophrenia is a heterogeneous disorder. Over the years, different approaches have been proposed to approach this heterogeneity by categorizing symptom patterns. The study aimed to compare positive/negative and system-specific approaches to subtyping. Methods We used the Positive and Negative Syndrome Scale (PANSS) and Bern Psychopathology Scale (BPS), which consists of subscales for three domains (language, affect and motor behavior) that are hypothesized to be related to specific brain circuits, to assess cross-sectional psychopathological characteristics in a sample of 100 inpatients with schizophrenia spectrum disorders. We then categorized participants into positive/negative and system-specific subgroups to allow comparisons of the two approaches. Results The analyses revealed correlations between the PANSS positive subscore and the BPS affective subscore (r =.446, p
AB - Background Schizophrenia is a heterogeneous disorder. Over the years, different approaches have been proposed to approach this heterogeneity by categorizing symptom patterns. The study aimed to compare positive/negative and system-specific approaches to subtyping. Methods We used the Positive and Negative Syndrome Scale (PANSS) and Bern Psychopathology Scale (BPS), which consists of subscales for three domains (language, affect and motor behavior) that are hypothesized to be related to specific brain circuits, to assess cross-sectional psychopathological characteristics in a sample of 100 inpatients with schizophrenia spectrum disorders. We then categorized participants into positive/negative and system-specific subgroups to allow comparisons of the two approaches. Results The analyses revealed correlations between the PANSS positive subscore and the BPS affective subscore (r =.446, p
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U2 - 10.1016/j.comppsych.2015.05.014
DO - 10.1016/j.comppsych.2015.05.014
M3 - Article
C2 - 26104431
AN - SCOPUS:84943657600
SN - 0010-440X
VL - 61
SP - 115
EP - 121
JO - Comprehensive Psychiatry
JF - Comprehensive Psychiatry
M1 - 51526
ER -