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Subtle Changes to Polymer Structure and Degradation Mechanism Enable Highly Effective Nanoparticles for siRNA and DNA Delivery to Human Brain Cancer
Stephany Y. Tzeng,
Jordan J. Green
School of Medicine
Research output
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Contribution to journal
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Article
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peer-review
68
Scopus citations
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Dive into the research topics of 'Subtle Changes to Polymer Structure and Degradation Mechanism Enable Highly Effective Nanoparticles for siRNA and DNA Delivery to Human Brain Cancer'. Together they form a unique fingerprint.
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Medicine & Life Sciences
Brain Neoplasms
71%
Polymers
68%
Nanoparticles
68%
Small Interfering RNA
64%
DNA
43%
Nucleic Acids
25%
poly(beta-amino ester)
23%
Transfection
22%
Cystamine
20%
Circular DNA
17%
Lipofectamine
17%
Biocompatible Materials
13%
Glioblastoma
12%
Molecular Weight
10%
Plasmids
10%
Genes
5%
Engineering & Materials Science
DNA
79%
Nanoparticles
75%
Brain
63%
Polymers
56%
Degradation
53%
Nucleic acids
32%
Cytotoxicity
16%
Functional groups
14%
Biomaterials
13%
Reagents
13%
Molecular weight
12%
Esters
12%
Cells
10%
Genes
10%
Materials properties
9%
Chemical Compounds
Nanoparticle
38%
Nucleic Acid
21%
Cystamine
18%
Molecular Weight (Polymers)
14%
Biomaterial
10%
Dose
9%
Ester
7%