TY - JOUR
T1 - Subthalamic nucleus involvement in children
T2 - A neuroimaging pattern-recognition approach
AU - Bosemani, Thangamadhan
AU - Anghelescu, Cristina
AU - Boltshauser, Eugen
AU - Hoon, Alexander H.
AU - Pearl, Phillip L.
AU - Craiu, Dana
AU - Johnston, Michael V.
AU - Huisman, Thierry A.G.M.
AU - Poretti, Andrea
PY - 2014/5
Y1 - 2014/5
N2 - A neuroimaging-based pattern-recognition approach has been shown to be very helpful in the diagnosis of a wide range of pediatric central nervous system diseases. Few disorders may selectively affect the subthalamic nucleus in children including Leigh syndrome, succinic semialdehyde dehydrogenase deficiency, kernicterus, chronic end-stage liver failure and near total hypoxic-ischemic injury in the full-term neonates. The consideration of the constellation of clinical history and findings as well as additional neuroimaging findings should allow planning the appropriate diagnostic tests to make the correct diagnosis in children with involvement of the subthalamic nucleus.
AB - A neuroimaging-based pattern-recognition approach has been shown to be very helpful in the diagnosis of a wide range of pediatric central nervous system diseases. Few disorders may selectively affect the subthalamic nucleus in children including Leigh syndrome, succinic semialdehyde dehydrogenase deficiency, kernicterus, chronic end-stage liver failure and near total hypoxic-ischemic injury in the full-term neonates. The consideration of the constellation of clinical history and findings as well as additional neuroimaging findings should allow planning the appropriate diagnostic tests to make the correct diagnosis in children with involvement of the subthalamic nucleus.
KW - Children
KW - Magnetic resonance imaging
KW - Pattern-recognition approach
KW - Subthalamic nucleus
UR - http://www.scopus.com/inward/record.url?scp=84900300005&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84900300005&partnerID=8YFLogxK
U2 - 10.1016/j.ejpn.2013.09.010
DO - 10.1016/j.ejpn.2013.09.010
M3 - Review article
C2 - 24149100
AN - SCOPUS:84900300005
SN - 1090-3798
VL - 18
SP - 249
EP - 256
JO - European Journal of Paediatric Neurology
JF - European Journal of Paediatric Neurology
IS - 3
ER -