Substrate specificity of human liver cytochrome P-450 debrisoquine 4-hydroxylase probed using immunochemical inhibition and chemical modeling

T. Wolff, L. M. Distlerath, M. T. Worthington, J. D. Groopman, G. J. Hammons, John Davis Groopman, R. A. Prough, M. V. Martin, F. P. Guengerich

Research output: Contribution to journalArticle

Original languageEnglish (US)
Pages (from-to)2116-2122
Number of pages7
JournalCancer Research
Volume45
Issue number5
StatePublished - 1985
Externally publishedYes

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Debrisoquin
Immunochemistry
Cytochrome P-450 CYP2D6
Aflatoxin B1
Aflatoxins
Liver Microsomes
Hydroxylation
Substrate Specificity
Mixed Function Oxygenases
Cytochrome P-450 Enzyme System
Liver
Antibodies
Methylation
1-Naphthylamine
2-Naphthylamine
Monocrotaline
Dimethylnitrosamine
Trichloroethylene
Benzo(a)pyrene
DNA

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Wolff, T., Distlerath, L. M., Worthington, M. T., Groopman, J. D., Hammons, G. J., Groopman, J. D., ... Guengerich, F. P. (1985). Substrate specificity of human liver cytochrome P-450 debrisoquine 4-hydroxylase probed using immunochemical inhibition and chemical modeling. Cancer Research, 45(5), 2116-2122.

Substrate specificity of human liver cytochrome P-450 debrisoquine 4-hydroxylase probed using immunochemical inhibition and chemical modeling. / Wolff, T.; Distlerath, L. M.; Worthington, M. T.; Groopman, J. D.; Hammons, G. J.; Groopman, John Davis; Prough, R. A.; Martin, M. V.; Guengerich, F. P.

In: Cancer Research, Vol. 45, No. 5, 1985, p. 2116-2122.

Research output: Contribution to journalArticle

Wolff, T, Distlerath, LM, Worthington, MT, Groopman, JD, Hammons, GJ, Groopman, JD, Prough, RA, Martin, MV & Guengerich, FP 1985, 'Substrate specificity of human liver cytochrome P-450 debrisoquine 4-hydroxylase probed using immunochemical inhibition and chemical modeling', Cancer Research, vol. 45, no. 5, pp. 2116-2122.
Wolff, T. ; Distlerath, L. M. ; Worthington, M. T. ; Groopman, J. D. ; Hammons, G. J. ; Groopman, John Davis ; Prough, R. A. ; Martin, M. V. ; Guengerich, F. P. / Substrate specificity of human liver cytochrome P-450 debrisoquine 4-hydroxylase probed using immunochemical inhibition and chemical modeling. In: Cancer Research. 1985 ; Vol. 45, No. 5. pp. 2116-2122.
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