Substantia nigra projections to the reticular formation, superior colliculus and central gray in the rat, cat and monkey

David A. Hopkins; Louis W. Niessen

doi:10.1016/0304-3940(76)90156-7

Substantia nigra projections to the reticular formation, superior colliculus and central gray in the rat, cat and monkey

David A. Hopkins, Louis W. Niessen

Research output: Contribution to journal › Article › peer-review

241 Scopus citations

Abstract

After horseradish peroxidase injections in different parts of the lower brain stem retrogradely labeled neurons were observed in the substantia nigra, mainly ipsilateral pars reticulata. These findings demonstrate that the substantia nigra projects not only to the striatum and thalamus but also to brain stem areas which give rise to descending spinal projections. These nigral projections to brain stem structures may play an important role in a variety of behaviors and may be involved in clinical syndromes associated with nigral lesions.

Original language	English (US)
Pages (from-to)	253-259
Number of pages	7
Journal	Neuroscience Letters
Volume	2
Issue number	5
DOIs	https://doi.org/10.1016/0304-3940(76)90156-7
State	Published - Jul 1976
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/0304-3940(76)90156-7

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title = "Substantia nigra projections to the reticular formation, superior colliculus and central gray in the rat, cat and monkey",

abstract = "After horseradish peroxidase injections in different parts of the lower brain stem retrogradely labeled neurons were observed in the substantia nigra, mainly ipsilateral pars reticulata. These findings demonstrate that the substantia nigra projects not only to the striatum and thalamus but also to brain stem areas which give rise to descending spinal projections. These nigral projections to brain stem structures may play an important role in a variety of behaviors and may be involved in clinical syndromes associated with nigral lesions.",

author = "Hopkins, {David A.} and Niessen, {Louis W.}",

note = "Funding Information: This investigation was supported in part by Grant 13-46-15 of the Dutch Organization for Fundamental Research in Medicine (FUNGO). We thank Drs. H.G.J.M. Kuypers and L. Moll for many helpful suggestions and Mr. E. Dalm, Miss P.C. Delfos, Mrs. E. Jongbloed-Klink, Miss F. Kwee and Mr. W. v.d. Oudenalder for technical assistance.",

year = "1976",

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doi = "10.1016/0304-3940(76)90156-7",

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T1 - Substantia nigra projections to the reticular formation, superior colliculus and central gray in the rat, cat and monkey

AU - Hopkins, David A.

AU - Niessen, Louis W.

N1 - Funding Information: This investigation was supported in part by Grant 13-46-15 of the Dutch Organization for Fundamental Research in Medicine (FUNGO). We thank Drs. H.G.J.M. Kuypers and L. Moll for many helpful suggestions and Mr. E. Dalm, Miss P.C. Delfos, Mrs. E. Jongbloed-Klink, Miss F. Kwee and Mr. W. v.d. Oudenalder for technical assistance.

PY - 1976/7

Y1 - 1976/7

N2 - After horseradish peroxidase injections in different parts of the lower brain stem retrogradely labeled neurons were observed in the substantia nigra, mainly ipsilateral pars reticulata. These findings demonstrate that the substantia nigra projects not only to the striatum and thalamus but also to brain stem areas which give rise to descending spinal projections. These nigral projections to brain stem structures may play an important role in a variety of behaviors and may be involved in clinical syndromes associated with nigral lesions.

AB - After horseradish peroxidase injections in different parts of the lower brain stem retrogradely labeled neurons were observed in the substantia nigra, mainly ipsilateral pars reticulata. These findings demonstrate that the substantia nigra projects not only to the striatum and thalamus but also to brain stem areas which give rise to descending spinal projections. These nigral projections to brain stem structures may play an important role in a variety of behaviors and may be involved in clinical syndromes associated with nigral lesions.

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Substantia nigra projections to the reticular formation, superior colliculus and central gray in the rat, cat and monkey

Abstract

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