Abstract
Substance abuse and addiction are highly prevalent in HIV-infected individuals. Substance abuse is an important comorbidity that affects the delivery and outcomes of HIV medical management. In this paper I will review data examining the associations between substance abuse and HIV treatment and potential strategies to improve outcomes in this population that warrant further investigation. Current - but not past - substance abuse adversely affects engagement in care, acceptance of antiretroviral therapy, adherence with therapy, and long-term persistence in care. Substance abuse treatment appears to facilitate engagement in HIV care, and access to evidence-based treatment for substance abuse is central to addressing the HIV epidemic. Strategies that show promise for HIV-infected substance abusers include integrated treatment models, directly observed therapy, and incentive-based interventions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 948-952 |
| Number of pages | 5 |
| Journal | Life Sciences |
| Volume | 88 |
| Issue number | 21-22 |
| DOIs | |
| State | Published - May 23 2011 |
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Keywords
- Addiction
- Adherence
- HIV infection
- Substance abuse
ASJC Scopus subject areas
- Pharmacology, Toxicology and Pharmaceutics(all)
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Substance abuse, adherence with antiretroviral therapy, and clinical outcomes among HIV-infected individuals. / Lucas, Gregory M.
In: Life Sciences, Vol. 88, No. 21-22, 23.05.2011, p. 948-952.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Substance abuse, adherence with antiretroviral therapy, and clinical outcomes among HIV-infected individuals
AU - Lucas, Gregory M
PY - 2011/5/23
Y1 - 2011/5/23
N2 - Substance abuse and addiction are highly prevalent in HIV-infected individuals. Substance abuse is an important comorbidity that affects the delivery and outcomes of HIV medical management. In this paper I will review data examining the associations between substance abuse and HIV treatment and potential strategies to improve outcomes in this population that warrant further investigation. Current - but not past - substance abuse adversely affects engagement in care, acceptance of antiretroviral therapy, adherence with therapy, and long-term persistence in care. Substance abuse treatment appears to facilitate engagement in HIV care, and access to evidence-based treatment for substance abuse is central to addressing the HIV epidemic. Strategies that show promise for HIV-infected substance abusers include integrated treatment models, directly observed therapy, and incentive-based interventions.
AB - Substance abuse and addiction are highly prevalent in HIV-infected individuals. Substance abuse is an important comorbidity that affects the delivery and outcomes of HIV medical management. In this paper I will review data examining the associations between substance abuse and HIV treatment and potential strategies to improve outcomes in this population that warrant further investigation. Current - but not past - substance abuse adversely affects engagement in care, acceptance of antiretroviral therapy, adherence with therapy, and long-term persistence in care. Substance abuse treatment appears to facilitate engagement in HIV care, and access to evidence-based treatment for substance abuse is central to addressing the HIV epidemic. Strategies that show promise for HIV-infected substance abusers include integrated treatment models, directly observed therapy, and incentive-based interventions.
KW - Addiction
KW - Adherence
KW - HIV infection
KW - Substance abuse
UR - http://www.scopus.com/inward/record.url?scp=79956192748&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79956192748&partnerID=8YFLogxK
U2 - 10.1016/j.lfs.2010.09.025
DO - 10.1016/j.lfs.2010.09.025
M3 - Article
C2 - 20888839
AN - SCOPUS:79956192748
VL - 88
SP - 948
EP - 952
JO - Life Sciences
JF - Life Sciences
SN - 0024-3205
IS - 21-22
ER -