Subdural recordings from an awake human brain for measuring current intensity during transcranial direct current stimulation

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Transcranial direct current stimulation (tDCS) is an emerging method, used for non-invasively stimulating the brain in normal healthy subjects and in patients with neurological disorders. However, the pattern of the spatial distribution of the current intensity induced by tDCS is poorly understood. In this study, we directly measured the spatial characteristics of the current intensity induced by tDCS using an intracranial strip electrode array implanted over the motor cortex in patients with Parkinson's disease undergoing deep brain stimulation lead placement surgery. We used a bilateral stimulation configuration for the tDCS electrode placement and measured the amount of electric current passing through the contacts along the implanted strip electrode contacts. Our results showed significant changes of the current flow induced by the tDCS in some of the contacts during stimulation with respect to baseline activities. These results may provide vital information regarding the biophysical effects of tDCS stimulation and might be potentially useful for developing more effective stimulation strategies.

Original languageEnglish (US)
Title of host publication2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publicationSmarter Technology for a Healthier World, EMBC 2017 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1110-1113
Number of pages4
ISBN (Electronic)9781509028092
DOIs
StatePublished - Sep 13 2017
Event39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017 - Jeju Island, Korea, Republic of
Duration: Jul 11 2017Jul 15 2017

Other

Other39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017
CountryKorea, Republic of
CityJeju Island
Period7/11/177/15/17

Fingerprint

Brain
Electrodes
Implanted Electrodes
Electric currents
Surgery
Spatial distribution
Deep Brain Stimulation
Motor Cortex
Nervous System Diseases
Parkinson Disease
Transcranial Direct Current Stimulation
Healthy Volunteers

Keywords

  • Deep brain stimulation
  • In vivo current measurement
  • Movement disorders
  • Parkinson's disease
  • Subdural strip electrodes
  • Transcranial direct current stimulation

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Salimpour, Y., Liu, C. C., Webber, W., Mills, K., & Anderson, W. S. (2017). Subdural recordings from an awake human brain for measuring current intensity during transcranial direct current stimulation. In 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings (pp. 1110-1113). [8037023] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2017.8037023

Subdural recordings from an awake human brain for measuring current intensity during transcranial direct current stimulation. / Salimpour, Yousef; Liu, Chang Chia; Webber, William; Mills, Kelly; Anderson, William S.

2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2017. p. 1110-1113 8037023.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Salimpour, Y, Liu, CC, Webber, W, Mills, K & Anderson, WS 2017, Subdural recordings from an awake human brain for measuring current intensity during transcranial direct current stimulation. in 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings., 8037023, Institute of Electrical and Electronics Engineers Inc., pp. 1110-1113, 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017, Jeju Island, Korea, Republic of, 7/11/17. https://doi.org/10.1109/EMBC.2017.8037023
Salimpour Y, Liu CC, Webber W, Mills K, Anderson WS. Subdural recordings from an awake human brain for measuring current intensity during transcranial direct current stimulation. In 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2017. p. 1110-1113. 8037023 https://doi.org/10.1109/EMBC.2017.8037023
Salimpour, Yousef ; Liu, Chang Chia ; Webber, William ; Mills, Kelly ; Anderson, William S. / Subdural recordings from an awake human brain for measuring current intensity during transcranial direct current stimulation. 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2017. pp. 1110-1113
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