Subcortical arteriosclerotic encephalopathy (Binswanger’s disease): A vascular etiology of dementia

Peter C. Burger, J. Gordon Burch, Ulf Kunze

Research output: Contribution to journalArticlepeer-review


A 51-year-old man with moderate intermittent hypertension had a rapidly progressive, profound dementia in the absence of significant localizing neurological signs. Postmortem examination disclosed the vascular alterations and diffuse white matter degeneration which characterize subcortical arteriosclerotic encephalopathy (SAE) or Binswanger’s disease. The case underscores the need to consider vascular disease as an etiology of dementia — even in the absence of focal neurological deficit.

Original languageEnglish (US)
Pages (from-to)626-631
Number of pages6
Issue number6
StatePublished - 1976
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing


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