Subcortical arteriosclerotic encephalopathy (Binswanger’s disease): A vascular etiology of dementia

Peter C. Burger; J. Gordon Burch; Ulf Kunze

doi:10.1161/01.STR.7.6.626

Subcortical arteriosclerotic encephalopathy (Binswanger’s disease): A vascular etiology of dementia

Peter C. Burger, J. Gordon Burch, Ulf Kunze

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54 Scopus citations

Abstract

A 51-year-old man with moderate intermittent hypertension had a rapidly progressive, profound dementia in the absence of significant localizing neurological signs. Postmortem examination disclosed the vascular alterations and diffuse white matter degeneration which characterize subcortical arteriosclerotic encephalopathy (SAE) or Binswanger’s disease. The case underscores the need to consider vascular disease as an etiology of dementia — even in the absence of focal neurological deficit.

Original language	English (US)
Pages (from-to)	626-631
Number of pages	6
Journal	Stroke
Volume	7
Issue number	6
DOIs	https://doi.org/10.1161/01.STR.7.6.626
State	Published - 1976
Externally published	Yes

ASJC Scopus subject areas

Clinical Neurology
Cardiology and Cardiovascular Medicine
Advanced and Specialized Nursing

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title = "Subcortical arteriosclerotic encephalopathy (Binswanger{\textquoteright}s disease): A vascular etiology of dementia",

abstract = "A 51-year-old man with moderate intermittent hypertension had a rapidly progressive, profound dementia in the absence of significant localizing neurological signs. Postmortem examination disclosed the vascular alterations and diffuse white matter degeneration which characterize subcortical arteriosclerotic encephalopathy (SAE) or Binswanger{\textquoteright}s disease. The case underscores the need to consider vascular disease as an etiology of dementia — even in the absence of focal neurological deficit.",

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AB - A 51-year-old man with moderate intermittent hypertension had a rapidly progressive, profound dementia in the absence of significant localizing neurological signs. Postmortem examination disclosed the vascular alterations and diffuse white matter degeneration which characterize subcortical arteriosclerotic encephalopathy (SAE) or Binswanger’s disease. The case underscores the need to consider vascular disease as an etiology of dementia — even in the absence of focal neurological deficit.

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Subcortical arteriosclerotic encephalopathy (Binswanger’s disease): A vascular etiology of dementia

Abstract

ASJC Scopus subject areas

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