TY - JOUR
T1 - Subclinical hyperthyroidism
AU - Biondi, Bernadette
AU - Cooper, David S
PY - 2018/6/21
Y1 - 2018/6/21
N2 - A 65-year-old woman is seen for routine evaluation. She has a history of paroxysmal atrial fibrillation and osteoporosis, which has been treated with a bisphosphonate. She has no history of thyroid disease and reports no symptoms of hyperthyroidism. Her pulse is 80 beats per minute. The left thyroid lobe is enlarged, but the results of physical examination are otherwise normal, as are the results of electrocardiography. The serum thyrotropin level is 0.2 mU per liter (reference range, 0.5 to 4.5) and the free thyroxine (T4) level 1.2 ng per deciliter (reference range, 0.8 to 1.8). How should this patient be evaluated and treated?
AB - A 65-year-old woman is seen for routine evaluation. She has a history of paroxysmal atrial fibrillation and osteoporosis, which has been treated with a bisphosphonate. She has no history of thyroid disease and reports no symptoms of hyperthyroidism. Her pulse is 80 beats per minute. The left thyroid lobe is enlarged, but the results of physical examination are otherwise normal, as are the results of electrocardiography. The serum thyrotropin level is 0.2 mU per liter (reference range, 0.5 to 4.5) and the free thyroxine (T4) level 1.2 ng per deciliter (reference range, 0.8 to 1.8). How should this patient be evaluated and treated?
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U2 - 10.1056/NEJMcp1709318
DO - 10.1056/NEJMcp1709318
M3 - Article
C2 - 29924956
AN - SCOPUS:85049222208
SN - 0028-4793
VL - 378
SP - 2411
EP - 2419
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 25
ER -