Subclassification of Clinical Stage T1 Prostate Cancer

Impact on Biochemical Recurrence Following Radical Prostatectomy

Ahmed Magheli, Soroush Rais-Bahrami, H Ballentine Carter, Hugh J. Peck, Jonathan Ira Epstein, Mark L. Gonzalgo

Research output: Contribution to journalArticle

Abstract

Purpose: We investigated biochemical outcomes following radical prostatectomy across subclassifications of clinical stage T1 prostate cancer. Material and Methods: Of 8,658 men who underwent radical prostatectomy for clinical stage T1 prostate cancer 85, 156 and 8,417 had clinical stage T1a, T1b and T1c disease, respectively. Age, race, prostate specific antigen, year of surgery and preoperative Gleason scores were compared across clinical stage T1 subcategories. Time to prostate specific antigen recurrence was compared among groups using Kaplan-Meier and Cox hazards modeling. Results: Patients with clinical stage T1a prostate cancer had more favorable postoperative pathological features, including lower prostatectomy Gleason scores (p

Original languageEnglish (US)
Pages (from-to)1277-1281
Number of pages5
JournalJournal of Urology
Volume178
Issue number4
DOIs
StatePublished - Oct 2007

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Prostatectomy
Prostatic Neoplasms
Neoplasm Grading
Prostate-Specific Antigen
Recurrence

Keywords

  • neoplasm staging
  • prostate
  • prostatectomy
  • prostatic neoplasms

ASJC Scopus subject areas

  • Urology

Cite this

Subclassification of Clinical Stage T1 Prostate Cancer : Impact on Biochemical Recurrence Following Radical Prostatectomy. / Magheli, Ahmed; Rais-Bahrami, Soroush; Carter, H Ballentine; Peck, Hugh J.; Epstein, Jonathan Ira; Gonzalgo, Mark L.

In: Journal of Urology, Vol. 178, No. 4, 10.2007, p. 1277-1281.

Research output: Contribution to journalArticle

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