Subacute sensory neuronopathy secondary to dorsal root ganglionitis in primary Sjogren's syndrome

K. Malinow, G. D. Yannakakis, S. M. Glusman, D. W. Edlow, J. Griffin, A. Pestronk, D. L. Powell, R. Ramsey-Goldman, B. H. Eidelman, T. A. Medsger

Research output: Contribution to journalArticle

Abstract

Sensory neuropathies, particularly trigeminal neuropathy, have been recognized as neurological complications of Sjogren's syndrome, but the pathogenesis has not been established. We describe a woman with primary Sjogren's syndrome who developed a progressive debilitating subacute sensory neuronopathy. Results of electrophysiological studies were consistent with involvement of the trigeminal and dorsal root ganglia. A thoracic dorsal root ganglion biopsy showed lymphocytic infiltration and degeneration of ganglion cells. We believe that this is the first description of biopsy-documented dorsal root ganglionitis in a subacute sensory neuronopathy associated with Sjogren's syndrome and that the finding suggests an immunopathogenic basis.

Original languageEnglish (US)
Pages (from-to)535-537
Number of pages3
JournalAnnals of Neurology
Volume20
Issue number4
StatePublished - 1986

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Spinal Nerve Roots
Sjogren's Syndrome
Spinal Ganglia
Trigeminal Nerve Diseases
Biopsy
Ganglia
Thorax

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Malinow, K., Yannakakis, G. D., Glusman, S. M., Edlow, D. W., Griffin, J., Pestronk, A., ... Medsger, T. A. (1986). Subacute sensory neuronopathy secondary to dorsal root ganglionitis in primary Sjogren's syndrome. Annals of Neurology, 20(4), 535-537.

Subacute sensory neuronopathy secondary to dorsal root ganglionitis in primary Sjogren's syndrome. / Malinow, K.; Yannakakis, G. D.; Glusman, S. M.; Edlow, D. W.; Griffin, J.; Pestronk, A.; Powell, D. L.; Ramsey-Goldman, R.; Eidelman, B. H.; Medsger, T. A.

In: Annals of Neurology, Vol. 20, No. 4, 1986, p. 535-537.

Research output: Contribution to journalArticle

Malinow, K, Yannakakis, GD, Glusman, SM, Edlow, DW, Griffin, J, Pestronk, A, Powell, DL, Ramsey-Goldman, R, Eidelman, BH & Medsger, TA 1986, 'Subacute sensory neuronopathy secondary to dorsal root ganglionitis in primary Sjogren's syndrome', Annals of Neurology, vol. 20, no. 4, pp. 535-537.
Malinow K, Yannakakis GD, Glusman SM, Edlow DW, Griffin J, Pestronk A et al. Subacute sensory neuronopathy secondary to dorsal root ganglionitis in primary Sjogren's syndrome. Annals of Neurology. 1986;20(4):535-537.
Malinow, K. ; Yannakakis, G. D. ; Glusman, S. M. ; Edlow, D. W. ; Griffin, J. ; Pestronk, A. ; Powell, D. L. ; Ramsey-Goldman, R. ; Eidelman, B. H. ; Medsger, T. A. / Subacute sensory neuronopathy secondary to dorsal root ganglionitis in primary Sjogren's syndrome. In: Annals of Neurology. 1986 ; Vol. 20, No. 4. pp. 535-537.
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