Studying sex and gender differences in pain and analgesia: A consensus report

Joel D. Greenspan; Rebecca M. Craft; Linda LeResche; Lars Arendt-Nielsen; Karen J. Berkley; Roger B. Fillingim; Michael S. Gold; Anita Holdcroft; Stefan Lautenbacher; Emeran A. Mayer; Jeffrey S. Mogil; Anne Z. Murphy; Richard J. Traub

doi:10.1016/j.pain.2007.10.014

Studying sex and gender differences in pain and analgesia: A consensus report

Joel D. Greenspan, Rebecca M. Craft, Linda LeResche, Lars Arendt-Nielsen, Karen J. Berkley, Roger B. Fillingim, Michael S. Gold, Anita Holdcroft, Stefan Lautenbacher, Emeran A. Mayer, Jeffrey S. Mogil, Anne Z. Murphy, Richard J. Traub

Research output: Contribution to journal › Review article › peer-review

620 Scopus citations

Abstract

In September 2006, members of the Sex, Gender and Pain Special Interest Group of the International Association for the Study of Pain met to discuss the following: (1) what is known about sex and gender differences in pain and analgesia; (2) what are the "best practice" guidelines for pain research with respect to sex and gender; and (3) what are the crucial questions to address in the near future? The resulting consensus presented herein includes input from basic science, clinical and psychosocial pain researchers, as well as from recognized experts in sexual differentiation and reproductive endocrinology. We intend this document to serve as a utilitarian and thought-provoking guide for future research on sex and gender differences in pain and analgesia, both for those currently working in this field as well as those still wondering, "Do I really need to study females?".

Original language	English (US)
Pages (from-to)	S26-S45
Journal	Pain
Volume	132
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1016/j.pain.2007.10.014
State	Published - Nov 2007
Externally published	Yes

Keywords

Estrogens
Gonadal hormones
Sex differences

ASJC Scopus subject areas

Neurology
Clinical Neurology
Anesthesiology and Pain Medicine

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10.1016/j.pain.2007.10.014

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title = "Studying sex and gender differences in pain and analgesia: A consensus report",

abstract = "In September 2006, members of the Sex, Gender and Pain Special Interest Group of the International Association for the Study of Pain met to discuss the following: (1) what is known about sex and gender differences in pain and analgesia; (2) what are the {"}best practice{"} guidelines for pain research with respect to sex and gender; and (3) what are the crucial questions to address in the near future? The resulting consensus presented herein includes input from basic science, clinical and psychosocial pain researchers, as well as from recognized experts in sexual differentiation and reproductive endocrinology. We intend this document to serve as a utilitarian and thought-provoking guide for future research on sex and gender differences in pain and analgesia, both for those currently working in this field as well as those still wondering, {"}Do I really need to study females?{"}.",

keywords = "Estrogens, Gonadal hormones, Sex differences",

author = "Greenspan, {Joel D.} and Craft, {Rebecca M.} and Linda LeResche and Lars Arendt-Nielsen and Berkley, {Karen J.} and Fillingim, {Roger B.} and Gold, {Michael S.} and Anita Holdcroft and Stefan Lautenbacher and Mayer, {Emeran A.} and Mogil, {Jeffrey S.} and Murphy, {Anne Z.} and Traub, {Richard J.}",

year = "2007",

month = nov,

doi = "10.1016/j.pain.2007.10.014",

language = "English (US)",

volume = "132",

pages = "S26--S45",

journal = "Pain",

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publisher = "Elsevier",

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AU - Greenspan, Joel D.

AU - Craft, Rebecca M.

AU - LeResche, Linda

AU - Arendt-Nielsen, Lars

AU - Berkley, Karen J.

AU - Fillingim, Roger B.

AU - Gold, Michael S.

AU - Holdcroft, Anita

AU - Lautenbacher, Stefan

AU - Mayer, Emeran A.

AU - Mogil, Jeffrey S.

AU - Murphy, Anne Z.

AU - Traub, Richard J.

PY - 2007/11

Y1 - 2007/11

N2 - In September 2006, members of the Sex, Gender and Pain Special Interest Group of the International Association for the Study of Pain met to discuss the following: (1) what is known about sex and gender differences in pain and analgesia; (2) what are the "best practice" guidelines for pain research with respect to sex and gender; and (3) what are the crucial questions to address in the near future? The resulting consensus presented herein includes input from basic science, clinical and psychosocial pain researchers, as well as from recognized experts in sexual differentiation and reproductive endocrinology. We intend this document to serve as a utilitarian and thought-provoking guide for future research on sex and gender differences in pain and analgesia, both for those currently working in this field as well as those still wondering, "Do I really need to study females?".

AB - In September 2006, members of the Sex, Gender and Pain Special Interest Group of the International Association for the Study of Pain met to discuss the following: (1) what is known about sex and gender differences in pain and analgesia; (2) what are the "best practice" guidelines for pain research with respect to sex and gender; and (3) what are the crucial questions to address in the near future? The resulting consensus presented herein includes input from basic science, clinical and psychosocial pain researchers, as well as from recognized experts in sexual differentiation and reproductive endocrinology. We intend this document to serve as a utilitarian and thought-provoking guide for future research on sex and gender differences in pain and analgesia, both for those currently working in this field as well as those still wondering, "Do I really need to study females?".

KW - Estrogens

KW - Gonadal hormones

KW - Sex differences

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VL - 132

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JO - Pain

JF - Pain

IS - SUPPL. 1

ER -

Studying sex and gender differences in pain and analgesia: A consensus report

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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