Study of parameters characterizing space-time Gibbs priors for 4D MAP-RBI-EM in gated myocardial perfusion SPECT

Taek-Soo Lee, W. Paul Segars, Benjamin Tsui

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We investigate the optimal parameters of the 4D space-time Gibbs priors used in the 4D MAP-RBI-EM method for application to gated myocardial perfusion (GMP) SPECT. The Gibbs prior can be defined by a clique structure, the derivative of a generalized potential function (DGPF) with 3 parameters, and the overall weight of the prior. We used simulated data from a realistic 4D NCAT phantom modeling the uptake distribution of Tc-99m Sestamibi and the detected counts of a typical GMP SPECT study. The cardiac cycle was divided into 8, 16, 24 and 36 gates with the same total acquisition time. The normalized mean squared error (NMSE) and normalized standard deviation (NSD) were used to describe the spatial and temporal resolution, and image noise magnitude, respectively. The optimized values were determined as those that minimize both NMSE and NSD simultaneously. The phantom-matching motion error (PME) was calculated for the motion error between the motions of the left ventricular (LV) wall in the reconstructed images and the corresponding phantom slices. The results show the 4D MAP-RBI-EM with optimized parameters provides substantial improved reconstructed image quality as compared to the 3D OS-EM method with and without correction of other image degrading factors. We conclude that the 4D MAP-RBI-EM provides significantly higher GMP SPECT image quality with less motion error thus enabling more number of cardiac gates in GMP SPECT resulting in better visualization of LV wall motion.

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposium Conference Record
Pages2124-2128
Number of pages5
Volume4
DOIs
StatePublished - 2005
EventNuclear Science Symposium Conference Record, 2005 IEEE - , Puerto Rico
Duration: Oct 23 2005Oct 29 2005

Other

OtherNuclear Science Symposium Conference Record, 2005 IEEE
CountryPuerto Rico
Period10/23/0510/29/05

Fingerprint

Image quality
Visualization
Derivatives

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering

Cite this

Study of parameters characterizing space-time Gibbs priors for 4D MAP-RBI-EM in gated myocardial perfusion SPECT. / Lee, Taek-Soo; Segars, W. Paul; Tsui, Benjamin.

IEEE Nuclear Science Symposium Conference Record. Vol. 4 2005. p. 2124-2128 1596754.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lee, T-S, Segars, WP & Tsui, B 2005, Study of parameters characterizing space-time Gibbs priors for 4D MAP-RBI-EM in gated myocardial perfusion SPECT. in IEEE Nuclear Science Symposium Conference Record. vol. 4, 1596754, pp. 2124-2128, Nuclear Science Symposium Conference Record, 2005 IEEE, Puerto Rico, 10/23/05. https://doi.org/10.1109/NSSMIC.2005.1596754
Lee, Taek-Soo ; Segars, W. Paul ; Tsui, Benjamin. / Study of parameters characterizing space-time Gibbs priors for 4D MAP-RBI-EM in gated myocardial perfusion SPECT. IEEE Nuclear Science Symposium Conference Record. Vol. 4 2005. pp. 2124-2128
@inproceedings{40abe2a073b846c298df9e993d850478,
title = "Study of parameters characterizing space-time Gibbs priors for 4D MAP-RBI-EM in gated myocardial perfusion SPECT",
abstract = "We investigate the optimal parameters of the 4D space-time Gibbs priors used in the 4D MAP-RBI-EM method for application to gated myocardial perfusion (GMP) SPECT. The Gibbs prior can be defined by a clique structure, the derivative of a generalized potential function (DGPF) with 3 parameters, and the overall weight of the prior. We used simulated data from a realistic 4D NCAT phantom modeling the uptake distribution of Tc-99m Sestamibi and the detected counts of a typical GMP SPECT study. The cardiac cycle was divided into 8, 16, 24 and 36 gates with the same total acquisition time. The normalized mean squared error (NMSE) and normalized standard deviation (NSD) were used to describe the spatial and temporal resolution, and image noise magnitude, respectively. The optimized values were determined as those that minimize both NMSE and NSD simultaneously. The phantom-matching motion error (PME) was calculated for the motion error between the motions of the left ventricular (LV) wall in the reconstructed images and the corresponding phantom slices. The results show the 4D MAP-RBI-EM with optimized parameters provides substantial improved reconstructed image quality as compared to the 3D OS-EM method with and without correction of other image degrading factors. We conclude that the 4D MAP-RBI-EM provides significantly higher GMP SPECT image quality with less motion error thus enabling more number of cardiac gates in GMP SPECT resulting in better visualization of LV wall motion.",
author = "Taek-Soo Lee and Segars, {W. Paul} and Benjamin Tsui",
year = "2005",
doi = "10.1109/NSSMIC.2005.1596754",
language = "English (US)",
isbn = "0780392213",
volume = "4",
pages = "2124--2128",
booktitle = "IEEE Nuclear Science Symposium Conference Record",

}

TY - GEN

T1 - Study of parameters characterizing space-time Gibbs priors for 4D MAP-RBI-EM in gated myocardial perfusion SPECT

AU - Lee, Taek-Soo

AU - Segars, W. Paul

AU - Tsui, Benjamin

PY - 2005

Y1 - 2005

N2 - We investigate the optimal parameters of the 4D space-time Gibbs priors used in the 4D MAP-RBI-EM method for application to gated myocardial perfusion (GMP) SPECT. The Gibbs prior can be defined by a clique structure, the derivative of a generalized potential function (DGPF) with 3 parameters, and the overall weight of the prior. We used simulated data from a realistic 4D NCAT phantom modeling the uptake distribution of Tc-99m Sestamibi and the detected counts of a typical GMP SPECT study. The cardiac cycle was divided into 8, 16, 24 and 36 gates with the same total acquisition time. The normalized mean squared error (NMSE) and normalized standard deviation (NSD) were used to describe the spatial and temporal resolution, and image noise magnitude, respectively. The optimized values were determined as those that minimize both NMSE and NSD simultaneously. The phantom-matching motion error (PME) was calculated for the motion error between the motions of the left ventricular (LV) wall in the reconstructed images and the corresponding phantom slices. The results show the 4D MAP-RBI-EM with optimized parameters provides substantial improved reconstructed image quality as compared to the 3D OS-EM method with and without correction of other image degrading factors. We conclude that the 4D MAP-RBI-EM provides significantly higher GMP SPECT image quality with less motion error thus enabling more number of cardiac gates in GMP SPECT resulting in better visualization of LV wall motion.

AB - We investigate the optimal parameters of the 4D space-time Gibbs priors used in the 4D MAP-RBI-EM method for application to gated myocardial perfusion (GMP) SPECT. The Gibbs prior can be defined by a clique structure, the derivative of a generalized potential function (DGPF) with 3 parameters, and the overall weight of the prior. We used simulated data from a realistic 4D NCAT phantom modeling the uptake distribution of Tc-99m Sestamibi and the detected counts of a typical GMP SPECT study. The cardiac cycle was divided into 8, 16, 24 and 36 gates with the same total acquisition time. The normalized mean squared error (NMSE) and normalized standard deviation (NSD) were used to describe the spatial and temporal resolution, and image noise magnitude, respectively. The optimized values were determined as those that minimize both NMSE and NSD simultaneously. The phantom-matching motion error (PME) was calculated for the motion error between the motions of the left ventricular (LV) wall in the reconstructed images and the corresponding phantom slices. The results show the 4D MAP-RBI-EM with optimized parameters provides substantial improved reconstructed image quality as compared to the 3D OS-EM method with and without correction of other image degrading factors. We conclude that the 4D MAP-RBI-EM provides significantly higher GMP SPECT image quality with less motion error thus enabling more number of cardiac gates in GMP SPECT resulting in better visualization of LV wall motion.

UR - http://www.scopus.com/inward/record.url?scp=33846594446&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846594446&partnerID=8YFLogxK

U2 - 10.1109/NSSMIC.2005.1596754

DO - 10.1109/NSSMIC.2005.1596754

M3 - Conference contribution

AN - SCOPUS:33846594446

SN - 0780392213

SN - 9780780392212

VL - 4

SP - 2124

EP - 2128

BT - IEEE Nuclear Science Symposium Conference Record

ER -