Study Design of Immunotherapy of Ragweed Allergy

William Franklin, W. J. Metzger, R. Patterson, J. J. Pruzansky, C. R. Zeiss, Philip S. Norman, Lawrence M. Lichtenstein

Research output: Contribution to journalLetter


To the Editor: The fine study of ragweed-allergy immunotherapy recently reported in the Journal1 is of great interest to those who treat allergic patients. Although polymerized antigens may ultimately prove of great value in atopic disorders, the conclusion that “polymerized antigen represents an improved form of immunotherapy that is as effective as standard immunotherapy” is not supported by the data available. Polymerized antigen E was compared with monomer antigen E and not with crude ragweed extract. The authors assumed that antigen E had been shown to be safer than crude ragweed antigen and to possess equal clinical efficacy. This.

Original languageEnglish (US)
Pages (from-to)573-574
Number of pages2
JournalNew England Journal of Medicine
Issue number10
StatePublished - Mar 10 1977


ASJC Scopus subject areas

  • Medicine(all)

Cite this

Franklin, W., Metzger, W. J., Patterson, R., Pruzansky, J. J., Zeiss, C. R., Norman, P. S., & Lichtenstein, L. M. (1977). Study Design of Immunotherapy of Ragweed Allergy. New England Journal of Medicine, 296(10), 573-574.