Studies on the Food Poisoning Associated with Putrefaction of Marine ProductsVi. Influence of Trimethylamine and Trimethylamine Oxide Added to Histamine or “Saurine” upon their Own Action in vivo

Toshiharu Kawabata, Kimishige Ishizaka, Toshiyuki Miura

Research output: Contribution to journalArticle


As shown in our previous paper, V, neither trimethylamine (TMA.) nor trimethylamine oxide C/rMAO) was described to have any recognizable synergism or; the action of histamine or “saurine” to contract intestine or uterus of guinea pigs. This paper also deals with the effect of those substances when added to histamine or “saurine “tested by shock symptoms in guinea pigs, skin reaction in rabbits and lethal dose for mice (LDsj-). The addition of TMA or TMAO resulted in no appreciable change in the action, of histamine of “saurine” per se in each experiment. Therefore, the presence of TMA or TMAO, if any, coaid not be regarded to stand as a cooperative factor tc either histamine or “saurine “in a foodstuff responsible for allergy-like food poisoning.

Original languageEnglish (US)
Pages (from-to)1177-1180
Number of pages4
JournalNippon Suisan Gakkaishi
Issue number11
StatePublished - 1956
Externally publishedYes


ASJC Scopus subject areas

  • Aquatic Science

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