Studies on the catabolism and distribution of fibrinogen in rats. Application of the iodogen® labelling technique

Mary E. Englert; M. Jane Landes; Jay E. Birnbaum; Arnold L. Oronsky; S. S. Kerwar

doi:10.1016/0006-291X(80)91242-5

Studies on the catabolism and distribution of fibrinogen in rats. Application of the iodogen® labelling technique

Mary E. Englert, M. Jane Landes, Jay E. Birnbaum, Arnold L. Oronsky, S. S. Kerwar

Research output: Contribution to journal › Article › peer-review

Abstract

The iodogen labelling technique has been applied to rat fibrinogen. Catabolism and body distributions of fibrinogen in the rat have been studied with fibrinogen labelled with 0.5 iodine atoms incorporated/mole of fibrinogen and biologically screened for 48 hours. Seventy-seven percent of fibrinogen body pool appeared to be localized intravascularly and a plasma half-life time of 23 hours has been found. The fractional catabolic rate was found to be 0.96/day under steady-state conditions.

Original language	English (US)
Pages (from-to)	49-55
Number of pages	7
Journal	Unknown Journal
Volume	97
Issue number	1
DOIs	https://doi.org/10.1016/0006-291X(80)91242-5
State	Published - 1980
Externally published	Yes

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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10.1016/0006-291X(80)91242-5

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title = "Studies on the catabolism and distribution of fibrinogen in rats. Application of the iodogen{\textregistered} labelling technique",

abstract = "The iodogen labelling technique has been applied to rat fibrinogen. Catabolism and body distributions of fibrinogen in the rat have been studied with fibrinogen labelled with 0.5 iodine atoms incorporated/mole of fibrinogen and biologically screened for 48 hours. Seventy-seven percent of fibrinogen body pool appeared to be localized intravascularly and a plasma half-life time of 23 hours has been found. The fractional catabolic rate was found to be 0.96/day under steady-state conditions.",

author = "Englert, {Mary E.} and Landes, {M. Jane} and Birnbaum, {Jay E.} and Oronsky, {Arnold L.} and Kerwar, {S. S.}",

year = "1980",

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AU - Englert, Mary E.

AU - Landes, M. Jane

AU - Birnbaum, Jay E.

AU - Oronsky, Arnold L.

AU - Kerwar, S. S.

PY - 1980

Y1 - 1980

N2 - The iodogen labelling technique has been applied to rat fibrinogen. Catabolism and body distributions of fibrinogen in the rat have been studied with fibrinogen labelled with 0.5 iodine atoms incorporated/mole of fibrinogen and biologically screened for 48 hours. Seventy-seven percent of fibrinogen body pool appeared to be localized intravascularly and a plasma half-life time of 23 hours has been found. The fractional catabolic rate was found to be 0.96/day under steady-state conditions.

AB - The iodogen labelling technique has been applied to rat fibrinogen. Catabolism and body distributions of fibrinogen in the rat have been studied with fibrinogen labelled with 0.5 iodine atoms incorporated/mole of fibrinogen and biologically screened for 48 hours. Seventy-seven percent of fibrinogen body pool appeared to be localized intravascularly and a plasma half-life time of 23 hours has been found. The fractional catabolic rate was found to be 0.96/day under steady-state conditions.

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JO - Unknown Journal

JF - Unknown Journal

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Studies on the catabolism and distribution of fibrinogen in rats. Application of the iodogen® labelling technique

Abstract

ASJC Scopus subject areas

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