Studies on the catabolism and distribution of fibrinogen in rats. Application of the iodogen® labelling technique

Mary E. Englert, M. Jane Landes, Jay E. Birnbaum, Arnold L. Oronsky, S. S. Kerwar

Research output: Contribution to journalArticlepeer-review

Abstract

The iodogen labelling technique has been applied to rat fibrinogen. Catabolism and body distributions of fibrinogen in the rat have been studied with fibrinogen labelled with 0.5 iodine atoms incorporated/mole of fibrinogen and biologically screened for 48 hours. Seventy-seven percent of fibrinogen body pool appeared to be localized intravascularly and a plasma half-life time of 23 hours has been found. The fractional catabolic rate was found to be 0.96/day under steady-state conditions.

Original languageEnglish (US)
Pages (from-to)49-55
Number of pages7
JournalUnknown Journal
Volume97
Issue number1
DOIs
StatePublished - 1980
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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