Studies on lens proteins from the smooth dogfish: Evidence for evolutionary conservatism in vertebrate β-crystallin

J. Samuel Zigler; J. B. Sidbury

doi:10.1159/000264871

Studies on lens proteins from the smooth dogfish: Evidence for evolutionary conservatism in vertebrate β-crystallin

J. Samuel Zigler, J. B. Sidbury

School of Medicine

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

The soluble lens proteins of the smooth dogfish (Mustelus canis) have been fractionated by gel filtration and partially characterized. A pattern of α-,β-, and low molecular weight crystallins similar to that of mammalian lens was found. Interestingly, only the dogfish β-crystallin fractions were found to cross-react with antiserum prepared against calf lens proteins.

Original language	English (US)
Pages (from-to)	92-98
Number of pages	7
Journal	Ophthalmic Research
Volume	9
Issue number	2
DOIs	https://doi.org/10.1159/000264871
State	Published - Jan 1 1977

Keywords

Dogfish lens proteins
Electrophoresis
Immunodiffusion
Isoelectric focusing
α-β-ϒ-crystallin

ASJC Scopus subject areas

Ophthalmology
Sensory Systems
Cellular and Molecular Neuroscience

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abstract = "The soluble lens proteins of the smooth dogfish (Mustelus canis) have been fractionated by gel filtration and partially characterized. A pattern of α-,β-, and low molecular weight crystallins similar to that of mammalian lens was found. Interestingly, only the dogfish β-crystallin fractions were found to cross-react with antiserum prepared against calf lens proteins.",

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author = "Zigler, {J. Samuel} and Sidbury, {J. B.}",

year = "1977",

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AB - The soluble lens proteins of the smooth dogfish (Mustelus canis) have been fractionated by gel filtration and partially characterized. A pattern of α-,β-, and low molecular weight crystallins similar to that of mammalian lens was found. Interestingly, only the dogfish β-crystallin fractions were found to cross-react with antiserum prepared against calf lens proteins.

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KW - Electrophoresis

KW - Immunodiffusion

KW - Isoelectric focusing

KW - α-β-ϒ-crystallin

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Studies on lens proteins from the smooth dogfish: Evidence for evolutionary conservatism in vertebrate β-crystallin

Abstract

Keywords

ASJC Scopus subject areas

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