Untersuchungen zum karotisbaroreflex bei schlafapnoepatienten

Translated title of the contribution: Studies on carotid baroreceptor reflex in obstructive sleep apnoea syndrome

J. J. Klawe, M. Tafil-Klawe, L. Grote, H. Schneider, J. H. Peter, M. Marcyniak, W. Szajnoch

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


15 patients (11 male, 9 female) with obstructive sleep apnoea syndrome (OSAS) and 10 healthy age- and weight-matched control subjects volunteered to participate in the study to test circadian variations of cardiac response to activation of carotid baroreceptors. Activation of carotid baroreceptors was evoked by applying a negative pressure to both left and right carotid sinus regions, using two small separate neck suction capsules. All experiments were performed under standard conditions every two hours. The cardiac response to carotid baroreceptors activation was significantly reduced in OSAS Patients, to a greater degree in the group of hypertensive patients. A characteristic circadian rhythm of baroreceptor reactivity persisted in all OSAS patients. Thus, OSAS patients constitute a high-risk group for the development of cardiovascular diseases and pathological course of blood pressure during daytime.

Translated title of the contributionStudies on carotid baroreceptor reflex in obstructive sleep apnoea syndrome
Original languageGerman
Pages (from-to)744-746
Number of pages3
Issue numberSUPPL. 3
StatePublished - Sep 16 1997

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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