Studies of insulin binding in children using human erythrocytes in small amounts of blood

M. S. Kappy, L. Plotnick

Research output: Contribution to journalArticle

Abstract

The authors have demonstrated specific insulin binding by the erythrocytes (RBCs) of children. Complete binding studies were done using as little as 5 ml of blood. The receptors exhibited competition-inhibition curves and nonlinear Scatchard plots similar to those reported for insulin target tissues, such as the hepatocyte and the adipocyte. Compared with those from adults, the RBCs from children had significantly greater numbers of insulin receptors per cell (P

Original languageEnglish (US)
Pages (from-to)1001-1005
Number of pages5
JournalDiabetes
Volume28
Issue number11
StatePublished - 1979

Fingerprint

Erythrocytes
Insulin
Insulin Receptor
Adipocytes
Hepatocytes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

Studies of insulin binding in children using human erythrocytes in small amounts of blood. / Kappy, M. S.; Plotnick, L.

In: Diabetes, Vol. 28, No. 11, 1979, p. 1001-1005.

Research output: Contribution to journalArticle

Kappy, MS & Plotnick, L 1979, 'Studies of insulin binding in children using human erythrocytes in small amounts of blood', Diabetes, vol. 28, no. 11, pp. 1001-1005.
Kappy, M. S. ; Plotnick, L. / Studies of insulin binding in children using human erythrocytes in small amounts of blood. In: Diabetes. 1979 ; Vol. 28, No. 11. pp. 1001-1005.
@article{946bb8b4dfd54a1bbc3cf1ee8793f964,
title = "Studies of insulin binding in children using human erythrocytes in small amounts of blood",
abstract = "The authors have demonstrated specific insulin binding by the erythrocytes (RBCs) of children. Complete binding studies were done using as little as 5 ml of blood. The receptors exhibited competition-inhibition curves and nonlinear Scatchard plots similar to those reported for insulin target tissues, such as the hepatocyte and the adipocyte. Compared with those from adults, the RBCs from children had significantly greater numbers of insulin receptors per cell (P",
author = "Kappy, {M. S.} and L. Plotnick",
year = "1979",
language = "English (US)",
volume = "28",
pages = "1001--1005",
journal = "Diabetes",
issn = "0012-1797",
publisher = "American Diabetes Association Inc.",
number = "11",

}

TY - JOUR

T1 - Studies of insulin binding in children using human erythrocytes in small amounts of blood

AU - Kappy, M. S.

AU - Plotnick, L.

PY - 1979

Y1 - 1979

N2 - The authors have demonstrated specific insulin binding by the erythrocytes (RBCs) of children. Complete binding studies were done using as little as 5 ml of blood. The receptors exhibited competition-inhibition curves and nonlinear Scatchard plots similar to those reported for insulin target tissues, such as the hepatocyte and the adipocyte. Compared with those from adults, the RBCs from children had significantly greater numbers of insulin receptors per cell (P

AB - The authors have demonstrated specific insulin binding by the erythrocytes (RBCs) of children. Complete binding studies were done using as little as 5 ml of blood. The receptors exhibited competition-inhibition curves and nonlinear Scatchard plots similar to those reported for insulin target tissues, such as the hepatocyte and the adipocyte. Compared with those from adults, the RBCs from children had significantly greater numbers of insulin receptors per cell (P

UR - http://www.scopus.com/inward/record.url?scp=0018597273&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018597273&partnerID=8YFLogxK

M3 - Article

C2 - 488537

AN - SCOPUS:0018597273

VL - 28

SP - 1001

EP - 1005

JO - Diabetes

JF - Diabetes

SN - 0012-1797

IS - 11

ER -