TY - JOUR
T1 - Structured review of post-cardiotomy extracorporeal membrane oxygenation
T2 - Part 2—pediatric patients
AU - Lorusso, Roberto
AU - Raffa, Giuseppe Maria
AU - Kowalewski, Mariusz
AU - Alenizy, Khalid
AU - Sluijpers, Niels
AU - Makhoul, Maged
AU - Brodie, Daniel
AU - McMullan, Mike
AU - Wang, I. Wen
AU - Meani, Paolo
AU - MacLaren, Graeme
AU - Dalton, Heidi
AU - Barbaro, Ryan
AU - Hou, Xaotong
AU - Cavarocchi, Nicholas
AU - Chen, Yih Sharng
AU - Thiagarajan, Ravi
AU - Alexander, Peta
AU - Alsoufi, Bahaaldin
AU - Bermudez, Christian A.
AU - Shah, Ashish S.
AU - Haft, Jonathan
AU - Oreto, Lilia
AU - D'Alessandro, David A.
AU - Boeken, Udo
AU - Whitman, Glenn
N1 - Publisher Copyright:
© 2019 International Society for Heart and Lung Transplantation
PY - 2019/11
Y1 - 2019/11
N2 - Veno-arterial extracorporeal membrane oxygenation (ECMO) is established therapy for short-term circulatory support for children with life-treating cardiorespiratory dysfunction. In children with congenital heart disease (CHD), ECMO is commonly used to support patients with post-cardiotomy shock or complications including intractable arrhythmias, cardiac arrest, and acute respiratory failure. Cannulation configurations include central, when the right atrium and aorta are utilized in patients with recent sternotomy, or peripheral, when cannulation of the neck or femoral vessels are used in non-operative patients. ECMO can be used to support any form of cardiac disease, including univentricular palliated circulation. Although veno-arterial ECMO is commonly used to support children with CHD, veno-venous ECMO has been used in selected patients with hypoxemia or ventilatory failure in the presence of good cardiac function. ECMO use and outcomes in the CHD population are mainly informed by single-center studies and reports from collated registry data. Significant knowledge gaps remain, including optimal patient selection, timing of ECMO deployment, duration of support, anti-coagulation, complications, and the impact of these factors on short- and long-term outcomes. This report, therefore, aims to present a comprehensive overview of the available literature informing patient selection, ECMO management, and in-hospital and early post-discharge outcomes in pediatric patients treated with ECMO for post-cardiotomy cardiorespiratory failure.
AB - Veno-arterial extracorporeal membrane oxygenation (ECMO) is established therapy for short-term circulatory support for children with life-treating cardiorespiratory dysfunction. In children with congenital heart disease (CHD), ECMO is commonly used to support patients with post-cardiotomy shock or complications including intractable arrhythmias, cardiac arrest, and acute respiratory failure. Cannulation configurations include central, when the right atrium and aorta are utilized in patients with recent sternotomy, or peripheral, when cannulation of the neck or femoral vessels are used in non-operative patients. ECMO can be used to support any form of cardiac disease, including univentricular palliated circulation. Although veno-arterial ECMO is commonly used to support children with CHD, veno-venous ECMO has been used in selected patients with hypoxemia or ventilatory failure in the presence of good cardiac function. ECMO use and outcomes in the CHD population are mainly informed by single-center studies and reports from collated registry data. Significant knowledge gaps remain, including optimal patient selection, timing of ECMO deployment, duration of support, anti-coagulation, complications, and the impact of these factors on short- and long-term outcomes. This report, therefore, aims to present a comprehensive overview of the available literature informing patient selection, ECMO management, and in-hospital and early post-discharge outcomes in pediatric patients treated with ECMO for post-cardiotomy cardiorespiratory failure.
KW - cardiac surgical procedures
KW - child
KW - congenital
KW - extracorporeal membrane oxygenation
KW - post-cardiotomy cardiogenic shock
KW - post-cardiotomy circulatory assistance
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U2 - 10.1016/j.healun.2019.07.004
DO - 10.1016/j.healun.2019.07.004
M3 - Article
C2 - 31421976
AN - SCOPUS:85070536118
SN - 1053-2498
VL - 38
SP - 1144
EP - 1161
JO - Journal of Heart and Lung Transplantation
JF - Journal of Heart and Lung Transplantation
IS - 11
ER -