Structure of a phage 434 Cro/DNA complex

Cynthia Wolberger, Yicheng Dong, Mark Ptashne, Stephen C. Harrison

Research output: Contribution to journalArticle


Comparison of the crystal structure of a complex of the phage 434 Cro protein and a synthetic DNA operator with the complex of the same operator and the 434 repressor DNA-binding domain shows different DNA conformations in the two structures. Binding of the protein determines the precise conformation of the DNA in each case.

Original languageEnglish (US)
Pages (from-to)789-795
Number of pages7
Issue number6193
StatePublished - Jan 1 1988


ASJC Scopus subject areas

  • General

Cite this

Wolberger, C., Dong, Y., Ptashne, M., & Harrison, S. C. (1988). Structure of a phage 434 Cro/DNA complex. Nature, 335(6193), 789-795.