Structure of a phage 434 Cro/DNA complex

Cynthia Wolberger, Yicheng Dong, Mark Ptashne, Stephen C. Harrison

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Abstract

Comparison of the crystal structure of a complex of the phage 434 Cro protein and a synthetic DNA operator with the complex of the same operator and the 434 repressor DNA-binding domain shows different DNA conformations in the two structures. Binding of the protein determines the precise conformation of the DNA in each case.

Original languageEnglish (US)
Pages (from-to)789-795
Number of pages7
JournalNature
Volume335
Issue number6193
DOIs
StatePublished - Jan 1 1988

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Wolberger, C., Dong, Y., Ptashne, M., & Harrison, S. C. (1988). Structure of a phage 434 Cro/DNA complex. Nature, 335(6193), 789-795. https://doi.org/10.1038/335789a0