Structure-Activity Relationship Studies of Cocaine: Replacement of the C-2 Ester Group by Vinyl Argues against H-Bonding and Provides an Esterase-Resistant, High-Affinity Cocaine Analogue

Alan P. Kozikowski, Marinella Roberti, Xiang Li Xiang, John S. Bergmann, Patrick M. Callahan, Kathryn A. Cunningham, Kenneth M. Johnson

Research output: Contribution to journalArticlepeer-review

Original languageEnglish (US)
Pages (from-to)4764-4766
Number of pages3
JournalJournal of medicinal chemistry
Volume35
Issue number25
DOIs
StatePublished - Dec 1 1992

ASJC Scopus subject areas

  • Molecular Medicine
  • Drug Discovery

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