Structural thermodynamics: Prediction of protein stability and protein binding affinities

Research output: Contribution to journalArticle

Abstract

The relationships between the structure of a protein and the thermodynamic parameters that determine its stability constitute the focus of attention of an increasing number of research laboratories. Advances in this area have reached the point in which accurate protein stability predictions and interaction energetics based on crystallographic information appear to be within reach. The purpose of this article is to summarize these developments and discuss future goals and trends.

Original languageEnglish (US)
Pages (from-to)181-184
Number of pages4
JournalArchives of Biochemistry and Biophysics
Volume303
Issue number2
DOIs
StatePublished - Jun 1993

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology

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