Stress testing and non-invasive coronary angiography in patients with suspected coronary artery disease: Time for a new paradigm

Research output: Contribution to journalReview articlepeer-review

Abstract

Diagnosis and management of coronary artery disease represents major challenges to our health care system, affecting millions of patients each year. Until recently, the diagnosis of coronary artery disease was possible only through cardiac catheterization and invasive coronary angiography. To avoid the risks of an invasive procedure, stress testing is often employed for an initial assessment of patients with suspected coronary artery disease, serving as a gatekeeper for cardiac catheterization. With the emergence of noninvasive coronary angiography, the question arises if such a strategy is still sensible, particularly, in view of only a modest agreement between stress testing results and the presence of coronary artery disease established by cardiac catheterization. Much data in support of the diagnostic accuracy and prognostic value of non-invasive coronary angiography by computed tomography have emerged within the last few years. These data challenge therole of stress testing as the initial imaging modality in patients with suspected coronary artery disease. This article reviews the clinical utility, limitations, as well as the hazards of stress testing compared with non-invasive coronary artery imaging by computed tomography. Finally, the implications of this review are discussed in relation to clinical practice.

Original languageEnglish (US)
Article numbere2
Pages (from-to)4-13
Number of pages10
JournalHeart International
Volume7
Issue number1
DOIs
StatePublished - 2012

Keywords

  • CT angiography
  • Cardiac CT
  • Coronary artery disease
  • Stress testing

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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