Stress and laterality - The comparative perspective

Sebastian Ocklenburg, S. Mechiel Korte, Jutta Peterburs, Oliver T. Wolf, Onur Güntürkün

Research output: Contribution to journalReview article

Abstract

Functional hemispheric asymmetries can vary over time and steroid hormones have been shown to be one of the factors that can modulate them. Research into this matter has mainly focused on sex steroid hormones (androgens, estrogens and progestogens), although there is increasing evidence that glucocorticoids which are related to the body's response to stress (e.g. cortisol or corticosterone) might also modulate functional hemispheric asymmetries. Here, we review studies in humans and non-human model species investigating the relation of stress and laterality. Results indicate a dual relationship of the two parameters. Both acute and chronic stress can affect different forms of lateralization in the human brain, often (but not always) resulting in greater involvement of the right hemisphere. Moreover, lateralization as a form of functional brain architecture can also represent a protective factor against adverse effects of stress.

Original languageEnglish (US)
Pages (from-to)321-329
Number of pages9
JournalPhysiology and Behavior
Volume164
DOIs
StatePublished - Oct 1 2016
Externally publishedYes

Fingerprint

Brain
Gonadal Steroid Hormones
Progestins
Corticosterone
Glucocorticoids
Androgens
Hydrocortisone
Estrogens
Steroids
Hormones
Research
Laterality
Protective Factors
Hemispheric Asymmetry
Lateralization
Right Hemisphere
Cortisol
Nonhuman
Estrogen

Keywords

  • Cortisol
  • Functional hemispheric asymmetries
  • Lateralization
  • Steroid hormones
  • Stress

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Philosophy
  • Behavioral Neuroscience

Cite this

Stress and laterality - The comparative perspective. / Ocklenburg, Sebastian; Korte, S. Mechiel; Peterburs, Jutta; Wolf, Oliver T.; Güntürkün, Onur.

In: Physiology and Behavior, Vol. 164, 01.10.2016, p. 321-329.

Research output: Contribution to journalReview article

Ocklenburg, Sebastian ; Korte, S. Mechiel ; Peterburs, Jutta ; Wolf, Oliver T. ; Güntürkün, Onur. / Stress and laterality - The comparative perspective. In: Physiology and Behavior. 2016 ; Vol. 164. pp. 321-329.
@article{00ea6940f90f4f0aaa086fd3cac8dc36,
title = "Stress and laterality - The comparative perspective",
abstract = "Functional hemispheric asymmetries can vary over time and steroid hormones have been shown to be one of the factors that can modulate them. Research into this matter has mainly focused on sex steroid hormones (androgens, estrogens and progestogens), although there is increasing evidence that glucocorticoids which are related to the body's response to stress (e.g. cortisol or corticosterone) might also modulate functional hemispheric asymmetries. Here, we review studies in humans and non-human model species investigating the relation of stress and laterality. Results indicate a dual relationship of the two parameters. Both acute and chronic stress can affect different forms of lateralization in the human brain, often (but not always) resulting in greater involvement of the right hemisphere. Moreover, lateralization as a form of functional brain architecture can also represent a protective factor against adverse effects of stress.",
keywords = "Cortisol, Functional hemispheric asymmetries, Lateralization, Steroid hormones, Stress",
author = "Sebastian Ocklenburg and Korte, {S. Mechiel} and Jutta Peterburs and Wolf, {Oliver T.} and Onur G{\"u}nt{\"u}rk{\"u}n",
year = "2016",
month = "10",
day = "1",
doi = "10.1016/j.physbeh.2016.06.020",
language = "English (US)",
volume = "164",
pages = "321--329",
journal = "Physiology and Behavior",
issn = "0031-9384",
publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Stress and laterality - The comparative perspective

AU - Ocklenburg, Sebastian

AU - Korte, S. Mechiel

AU - Peterburs, Jutta

AU - Wolf, Oliver T.

AU - Güntürkün, Onur

PY - 2016/10/1

Y1 - 2016/10/1

N2 - Functional hemispheric asymmetries can vary over time and steroid hormones have been shown to be one of the factors that can modulate them. Research into this matter has mainly focused on sex steroid hormones (androgens, estrogens and progestogens), although there is increasing evidence that glucocorticoids which are related to the body's response to stress (e.g. cortisol or corticosterone) might also modulate functional hemispheric asymmetries. Here, we review studies in humans and non-human model species investigating the relation of stress and laterality. Results indicate a dual relationship of the two parameters. Both acute and chronic stress can affect different forms of lateralization in the human brain, often (but not always) resulting in greater involvement of the right hemisphere. Moreover, lateralization as a form of functional brain architecture can also represent a protective factor against adverse effects of stress.

AB - Functional hemispheric asymmetries can vary over time and steroid hormones have been shown to be one of the factors that can modulate them. Research into this matter has mainly focused on sex steroid hormones (androgens, estrogens and progestogens), although there is increasing evidence that glucocorticoids which are related to the body's response to stress (e.g. cortisol or corticosterone) might also modulate functional hemispheric asymmetries. Here, we review studies in humans and non-human model species investigating the relation of stress and laterality. Results indicate a dual relationship of the two parameters. Both acute and chronic stress can affect different forms of lateralization in the human brain, often (but not always) resulting in greater involvement of the right hemisphere. Moreover, lateralization as a form of functional brain architecture can also represent a protective factor against adverse effects of stress.

KW - Cortisol

KW - Functional hemispheric asymmetries

KW - Lateralization

KW - Steroid hormones

KW - Stress

UR - http://www.scopus.com/inward/record.url?scp=84975045767&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84975045767&partnerID=8YFLogxK

U2 - 10.1016/j.physbeh.2016.06.020

DO - 10.1016/j.physbeh.2016.06.020

M3 - Review article

C2 - 27321757

AN - SCOPUS:84975045767

VL - 164

SP - 321

EP - 329

JO - Physiology and Behavior

JF - Physiology and Behavior

SN - 0031-9384

ER -