Strategic plan for pediatric respiratory diseases research: An NHLBI working group report

Mario Castro; Maria I. Ramirez; James E. Gern; Garry Cutting; Greg Redding; James S. Hagood; Jeffrey Whitsett; Steve Abman; J. Usha Raj; Robyn Barst; Gregory J. Kato; David Gozal; Gabriel G. Haddad; Nanduri R. Prabhakar; Estelle Gauda; Fernando D. Martinez; Robert Tepper; Robert E. Wood; Frank Accurso; W. Gerald Teague; Jose Venegas; F. Sessions Cole; Rosalind J. Wright; Carol J. Blaisdell

doi:10.1002/ppul.20973

Strategic plan for pediatric respiratory diseases research: An NHLBI working group report

Mario Castro, Maria I. Ramirez, James E. Gern, Garry Cutting, Greg Redding, James S. Hagood, Jeffrey Whitsett, Steve Abman, J. Usha Raj, Robyn Barst, Gregory J. Kato, David Gozal, Gabriel G. Haddad, Nanduri R. Prabhakar, Estelle Gauda, Fernando D. Martinez, Robert Tepper, Robert E. Wood, Frank Accurso, W. Gerald TeagueJose Venegas, F. Sessions Cole, Rosalind J. Wright, Carol J. Blaisdell

School of Medicine

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The Division of Lung Diseases of the National Heart, Lung and Blood Institute (NHLBI) recently held a workshop to identify gaps in our understanding and treatment of childhood lung diseases and to define strategies to enhance translational research in this field. Leading experts with diverse experience in both laboratory and patient-oriented research reviewed selected areas of pediatric lung diseases, including perinatal programming and epigenetic influences; mechanisms of lung injury, repair, and regeneration; pulmonary vascular disease (PVD); sleep and control of breathing; and the application of novel translational methods to enhance personalized medicine. This report summarizes the proceedings of this workshop and provides recommendations for emphasis on targeted areas for future investigation. The priority areas identified for research in pediatric pulmonary diseases included: (1) epigenetic and environmental influences on lung development that program pediatric lung diseases, (2) injury, regeneration, and repair in the developing lung, (3) PVD in children, (4) development and adaptation of ventilatory responses to postnatal life, (5) nonatopic wheezing: aberrant large airway development or injury? (6) strategies to improve assessment, diagnosis, and treatment of pediatric respiratory diseases, and (7) predictive and personalized medicine for children.

Original language	English (US)
Pages (from-to)	2-13
Number of pages	12
Journal	Pediatric pulmonology
Volume	44
Issue number	1
DOIs	https://doi.org/10.1002/ppul.20973
State	Published - Jan 2009

Keywords

Epigenetics
Lung disease
Pediatric
Respiratory

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Pulmonary and Respiratory Medicine

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10.1002/ppul.20973

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Castro, M., Ramirez, M. I., Gern, J. E., Cutting, G., Redding, G., Hagood, J. S., Whitsett, J., Abman, S., Usha Raj, J., Barst, R., Kato, G. J., Gozal, D., Haddad, G. G., Prabhakar, N. R., Gauda, E., Martinez, F. D., Tepper, R., Wood, R. E., Accurso, F., ... Blaisdell, C. J. (2009). Strategic plan for pediatric respiratory diseases research: An NHLBI working group report. Pediatric pulmonology, 44(1), 2-13. https://doi.org/10.1002/ppul.20973

Castro, M, Ramirez, MI, Gern, JE, Cutting, G, Redding, G, Hagood, JS, Whitsett, J, Abman, S, Usha Raj, J, Barst, R, Kato, GJ, Gozal, D, Haddad, GG, Prabhakar, NR, Gauda, E, Martinez, FD, Tepper, R, Wood, RE, Accurso, F, Gerald Teague, W, Venegas, J, Sessions Cole, F, Wright, RJ & Blaisdell, CJ 2009, 'Strategic plan for pediatric respiratory diseases research: An NHLBI working group report', Pediatric pulmonology, vol. 44, no. 1, pp. 2-13. https://doi.org/10.1002/ppul.20973

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Strategic plan for pediatric respiratory diseases research: An NHLBI working group report

Abstract

Keywords

ASJC Scopus subject areas

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