Sterols for oxygen: The metabolic burden of microbial SREBP

Research output: Contribution to journalShort surveypeer-review

4 Scopus citations


In this issue of Molecular Cell, Lee et al. (2011) report a novel mechanism for oxygen-sensing in S. pombe, whereby the 2-OG-Fe(II) dioxygenase Ofd protein regulates both the DNA-binding activity and the degradation of the hypoxia regulated transcription factor, Sre1p.

Original languageEnglish (US)
Pages (from-to)172-174
Number of pages3
JournalMolecular cell
Issue number2
StatePublished - Oct 21 2011
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology


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