Sterols for oxygen: The metabolic burden of microbial SREBP

Timothy F. Osborne

doi:10.1016/j.molcel.2011.10.004

Sterols for oxygen: The metabolic burden of microbial SREBP

Timothy F. Osborne

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

In this issue of Molecular Cell, Lee et al. (2011) report a novel mechanism for oxygen-sensing in S. pombe, whereby the 2-OG-Fe(II) dioxygenase Ofd protein regulates both the DNA-binding activity and the degradation of the hypoxia regulated transcription factor, Sre1p.

Original language	English (US)
Pages (from-to)	172-174
Number of pages	3
Journal	Molecular cell
Volume	44
Issue number	2
DOIs	https://doi.org/10.1016/j.molcel.2011.10.004
State	Published - Oct 21 2011
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1016/j.molcel.2011.10.004

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title = "Sterols for oxygen: The metabolic burden of microbial SREBP",

abstract = "In this issue of Molecular Cell, Lee et al. (2011) report a novel mechanism for oxygen-sensing in S. pombe, whereby the 2-OG-Fe(II) dioxygenase Ofd protein regulates both the DNA-binding activity and the degradation of the hypoxia regulated transcription factor, Sre1p.",

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year = "2011",

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AU - Osborne, Timothy F.

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AB - In this issue of Molecular Cell, Lee et al. (2011) report a novel mechanism for oxygen-sensing in S. pombe, whereby the 2-OG-Fe(II) dioxygenase Ofd protein regulates both the DNA-binding activity and the degradation of the hypoxia regulated transcription factor, Sre1p.

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DO - 10.1016/j.molcel.2011.10.004

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JO - Molecular cell

JF - Molecular cell

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Sterols for oxygen: The metabolic burden of microbial SREBP

Abstract

ASJC Scopus subject areas

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