Stereotactic radiation therapy combined with immunotherapy: augmenting the role of radiation in local and systemic treatment

Andrew B. Sharabi, Phuoc T. Tran, Michael Lim, Charles G. Drake, Theodore L. Deweese

Research output: Contribution to journalArticle

Abstract

Stereotactic radiosurgery and stereotactic body radiation therapy are two contemporary radiation modalities that can treat tumors in any area of the body using highly focused radiation. Recently, immunotherapy has established itself as a viable and powerful anticancer treatment. In this review we detail the rationale supporting a combination of immunotherapy and stereotactic radiation. Additionally, we discuss the evidence for the immune stimulatory effects of focused radiation and the role that radiation may play in enhancing the systemic treatment effects of immunotherapy.

Original languageEnglish (US)
Pages (from-to)331-340
Number of pages10
JournalOncology
Volume29
Issue number5
StatePublished - May 1 2015
Externally publishedYes

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Immunotherapy
Radiotherapy
Radiation
Radiosurgery
Radiation Effects
Therapeutics
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Stereotactic radiation therapy combined with immunotherapy : augmenting the role of radiation in local and systemic treatment. / Sharabi, Andrew B.; Tran, Phuoc T.; Lim, Michael; Drake, Charles G.; Deweese, Theodore L.

In: Oncology, Vol. 29, No. 5, 01.05.2015, p. 331-340.

Research output: Contribution to journalArticle

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