Abstract
The synthesis of the C2 and C3 epimer and also the enantiomer of jaspine B from d-glucose is reported. The cytotoxicity of these isomers along with jaspine B and its C2 epimer on MCF7 cells has been correlated with commercially available anticancer drug Epirubicin.
Original language | English (US) |
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Pages (from-to) | 115-119 |
Number of pages | 5 |
Journal | Synthesis |
Issue number | 1 |
DOIs | |
State | Published - 2010 |
Externally published | Yes |
Keywords
- Cytotoxicity
- D-glucose
- Jaspine B
- Mitsunobu inversion
- Pachastrissamine
- Wittig olefination
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry