Stem cell transplantation in neurodegenerative disorders of the gastrointestinal tract

Future or fiction?

Research output: Contribution to journalArticle

Abstract

Current advances in our understanding of stem and precursor cell biology and in the protocols of stem cell isolation and transplantation have opened up the possibility of transplanting neural stem cells for the treatment of gastrointestinal motility disorders. This review summarises the current status of research in this field, identifies the major gaps in our knowledge and discusses the potential opportunities and hurdles for clinical application.

Original languageEnglish (US)
Pages (from-to)613-621
Number of pages9
JournalGut
Volume61
Issue number4
DOIs
StatePublished - Apr 2012
Externally publishedYes

Fingerprint

Gastrointestinal Motility
Neural Stem Cells
Cell Separation
Stem Cell Transplantation
Neurodegenerative Diseases
Cell Biology
Gastrointestinal Tract
Stem Cells
Research
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Stem cell transplantation in neurodegenerative disorders of the gastrointestinal tract : Future or fiction? / Kulkarni, Subhash; Becker, Laren; Pasricha, Pankaj Jay.

In: Gut, Vol. 61, No. 4, 04.2012, p. 613-621.

Research output: Contribution to journalArticle

@article{affe8b3f9c924ad3bfed2980cc9ef7a3,
title = "Stem cell transplantation in neurodegenerative disorders of the gastrointestinal tract: Future or fiction?",
abstract = "Current advances in our understanding of stem and precursor cell biology and in the protocols of stem cell isolation and transplantation have opened up the possibility of transplanting neural stem cells for the treatment of gastrointestinal motility disorders. This review summarises the current status of research in this field, identifies the major gaps in our knowledge and discusses the potential opportunities and hurdles for clinical application.",
author = "Subhash Kulkarni and Laren Becker and Pasricha, {Pankaj Jay}",
year = "2012",
month = "4",
doi = "10.1136/gut.2010.235614",
language = "English (US)",
volume = "61",
pages = "613--621",
journal = "Gut",
issn = "0017-5749",
publisher = "BMJ Publishing Group",
number = "4",

}

TY - JOUR

T1 - Stem cell transplantation in neurodegenerative disorders of the gastrointestinal tract

T2 - Future or fiction?

AU - Kulkarni, Subhash

AU - Becker, Laren

AU - Pasricha, Pankaj Jay

PY - 2012/4

Y1 - 2012/4

N2 - Current advances in our understanding of stem and precursor cell biology and in the protocols of stem cell isolation and transplantation have opened up the possibility of transplanting neural stem cells for the treatment of gastrointestinal motility disorders. This review summarises the current status of research in this field, identifies the major gaps in our knowledge and discusses the potential opportunities and hurdles for clinical application.

AB - Current advances in our understanding of stem and precursor cell biology and in the protocols of stem cell isolation and transplantation have opened up the possibility of transplanting neural stem cells for the treatment of gastrointestinal motility disorders. This review summarises the current status of research in this field, identifies the major gaps in our knowledge and discusses the potential opportunities and hurdles for clinical application.

UR - http://www.scopus.com/inward/record.url?scp=84857798175&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84857798175&partnerID=8YFLogxK

U2 - 10.1136/gut.2010.235614

DO - 10.1136/gut.2010.235614

M3 - Article

VL - 61

SP - 613

EP - 621

JO - Gut

JF - Gut

SN - 0017-5749

IS - 4

ER -