Stem cell therapy

Promising treatment in heart failure?

John H. Loughran, Atul R. Chugh, Imtiaz Ismail, Roberto Bolli

Research output: Contribution to journalArticle

Abstract

Cardiac repair through the use of regenerative medicine has been a considerable research focus over the last decade. Several stem cell types have been investigated over this timeframe as potential candidates to target post-infarction heart failure. The progression of investigation through the rigors of clinical trial design has provided some answers as to the potential clinical utility of this therapy; although there are many questions that remain. This review will concentrate on the clinical trial results of stem cell therapy for cardiac repair since the turn of the century and discuss some of the points that need clarification before this form of therapy can be considered for widespread applicability.

Original languageEnglish (US)
Pages (from-to)73-80
Number of pages8
JournalCurrent Heart Failure Reports
Volume10
Issue number1
DOIs
StatePublished - 2013
Externally publishedYes

Fingerprint

Cell- and Tissue-Based Therapy
Stem Cells
Heart Failure
Clinical Trials
Regenerative Medicine
Infarction
Therapeutics
Research

Keywords

  • Bone-marrow mononuclear stem cells
  • CAD
  • Chronic ischemic heart disease
  • Myogenesis
  • Stem cell therapy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)
  • Emergency Medicine

Cite this

Stem cell therapy : Promising treatment in heart failure? / Loughran, John H.; Chugh, Atul R.; Ismail, Imtiaz; Bolli, Roberto.

In: Current Heart Failure Reports, Vol. 10, No. 1, 2013, p. 73-80.

Research output: Contribution to journalArticle

Loughran, JH, Chugh, AR, Ismail, I & Bolli, R 2013, 'Stem cell therapy: Promising treatment in heart failure?', Current Heart Failure Reports, vol. 10, no. 1, pp. 73-80. https://doi.org/10.1007/s11897-012-0128-2
Loughran, John H. ; Chugh, Atul R. ; Ismail, Imtiaz ; Bolli, Roberto. / Stem cell therapy : Promising treatment in heart failure?. In: Current Heart Failure Reports. 2013 ; Vol. 10, No. 1. pp. 73-80.
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