Stem cell therapy: MRI guidance and monitoring

Dara L. Kraitchman; Wesley D. Gilson; Christine H. Lorenz

doi:10.1002/jmri.21263

Stem cell therapy: MRI guidance and monitoring

Dara L. Kraitchman, Wesley D. Gilson, Christine H. Lorenz

School of Medicine

Research output: Contribution to journal › Review article › peer-review

61 Scopus citations

Abstract

With the recent advances in magnetic resonance (MR) labeling of cellular therapeutics, it is natural that interventional MRI techniques for targeting would be developed. This review provides an overview of the current methods of stem cell labeling and the challenges that are created with respect to interventional MRI administration. In particular, stem cell therapies will require specialized, MR-compatible devices as well as integration of graphical user interfaces with pulse sequences designed for interactive, real-time delivery in many organs. Specific applications that are being developed will be reviewed as well as strategies for future translation to the clinical realm.

Original language	English (US)
Pages (from-to)	299-310
Number of pages	12
Journal	Journal of Magnetic Resonance Imaging
Volume	27
Issue number	2
DOIs	https://doi.org/10.1002/jmri.21263
State	Published - Feb 2008

Keywords

Cardiac
Interventional MRI
Stem cells

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1002/jmri.21263

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title = "Stem cell therapy: MRI guidance and monitoring",

abstract = "With the recent advances in magnetic resonance (MR) labeling of cellular therapeutics, it is natural that interventional MRI techniques for targeting would be developed. This review provides an overview of the current methods of stem cell labeling and the challenges that are created with respect to interventional MRI administration. In particular, stem cell therapies will require specialized, MR-compatible devices as well as integration of graphical user interfaces with pulse sequences designed for interactive, real-time delivery in many organs. Specific applications that are being developed will be reviewed as well as strategies for future translation to the clinical realm.",

keywords = "Cardiac, Interventional MRI, Stem cells",

author = "Kraitchman, {Dara L.} and Gilson, {Wesley D.} and Lorenz, {Christine H.}",

year = "2008",

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AU - Gilson, Wesley D.

AU - Lorenz, Christine H.

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N2 - With the recent advances in magnetic resonance (MR) labeling of cellular therapeutics, it is natural that interventional MRI techniques for targeting would be developed. This review provides an overview of the current methods of stem cell labeling and the challenges that are created with respect to interventional MRI administration. In particular, stem cell therapies will require specialized, MR-compatible devices as well as integration of graphical user interfaces with pulse sequences designed for interactive, real-time delivery in many organs. Specific applications that are being developed will be reviewed as well as strategies for future translation to the clinical realm.

AB - With the recent advances in magnetic resonance (MR) labeling of cellular therapeutics, it is natural that interventional MRI techniques for targeting would be developed. This review provides an overview of the current methods of stem cell labeling and the challenges that are created with respect to interventional MRI administration. In particular, stem cell therapies will require specialized, MR-compatible devices as well as integration of graphical user interfaces with pulse sequences designed for interactive, real-time delivery in many organs. Specific applications that are being developed will be reviewed as well as strategies for future translation to the clinical realm.

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KW - Interventional MRI

KW - Stem cells

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Stem cell therapy: MRI guidance and monitoring

Abstract

Keywords

ASJC Scopus subject areas

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