Statistical Considerations in Analysis and Interpretation of Biomarker Studies

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Here we discuss traditional and emerging statistical methods for evaluating the prediction performance of biomarkers. We highlight considerations for planning a study and discuss unique statistical considerations when executing studies assessing biomarker performance including appropriate metrics to quantify biomarker-prediction performance and sample-size estimation.

Original languageEnglish (US)
Title of host publicationBiomarkers of Kidney Disease
PublisherElsevier Inc.
Pages21-32
Number of pages12
ISBN (Print)9780128030141
DOIs
StatePublished - Jan 1 2017

Keywords

  • Accuracy
  • False positive rate
  • Incremental value
  • ROC curves
  • True positive rate

ASJC Scopus subject areas

  • Medicine(all)

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