TY - GEN
T1 - Statistical atlases and machine learning tools applied to optimized prostate biopsy for cancer detection and estimation of volume and Gleason score
AU - Davatzikos, Christos
PY - 2011/11/2
Y1 - 2011/11/2
N2 - We discuss the use of statistical atlases and machine learning tools for determining optimized biopsy procedures. Prostate cancer diagnosis most often involves the sampling of prostate tissue via placement of a number of biopsy needles in locations that are somewhat random but try to cover the gland. The purpose of this work is to establish optimal strategies for sampling the prostate tissue, using population statistics. In particular, a statistical atlas reflecting the spatial distribution of prostate cancer has been constructed via elastic registration of expert-labeled histological 3D volumes of radical prostatectomy patients[1]. This atlas reflects the probability of encountering prostate carcinoma at a given location in the gland.
AB - We discuss the use of statistical atlases and machine learning tools for determining optimized biopsy procedures. Prostate cancer diagnosis most often involves the sampling of prostate tissue via placement of a number of biopsy needles in locations that are somewhat random but try to cover the gland. The purpose of this work is to establish optimal strategies for sampling the prostate tissue, using population statistics. In particular, a statistical atlas reflecting the spatial distribution of prostate cancer has been constructed via elastic registration of expert-labeled histological 3D volumes of radical prostatectomy patients[1]. This atlas reflects the probability of encountering prostate carcinoma at a given location in the gland.
KW - prostate biopsy
KW - statistical atlas of prostate cancer
KW - statistical models
UR - http://www.scopus.com/inward/record.url?scp=80055042007&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80055042007&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2011.5872828
DO - 10.1109/ISBI.2011.5872828
M3 - Conference contribution
AN - SCOPUS:80055042007
SN - 9781424441280
T3 - Proceedings - International Symposium on Biomedical Imaging
SP - 2107
EP - 2108
BT - 2011 8th IEEE International Symposium on Biomedical Imaging
T2 - 2011 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI'11
Y2 - 30 March 2011 through 2 April 2011
ER -