STAT3 activation is required for cell transformation and survival mediated by Asp⁸¹⁶ mutant c-Kit

Medicine & Life Sciences

• Cell Survival 89%
• Leukemia 43%
• Acute Myeloid Leukemia 37%
• Myeloid Cells 26%
• Cytokines 24%
• Mutation 22%
• Complementary DNA 21%
• Mastocytosis 18%
• Apoptosis 16%
• Germ Cell and Embryonal Neoplasms 15%
• HEK293 Cells 14%
• Transducers 13%
• Growth 13%
• Codon 12%
• Drug Resistance 12%
• Transcriptional Activation 11%
• Heterografts 11%
• Transfection 11%
• Pharmaceutical Preparations 10%
• Signal Transduction 10%
• Cell Line 7%

Chemical Compounds

• Mutation 100%
• Chemical Transformation 74%
• Signal Transduction 42%
• Complementary DNA 41%
• Antineoplastic Agent 34%
• Protective 32%
• Resistance 24%