Staged hepatectomy for bilobar colorectal hepatic metastases

Mohammad H. Jamal, Mazen Hassanain, Prosanto Chaudhury, Tung T. Tran, Stephanie Wong, Yasmine Yousef, Yelda Jozaghi, Ayat Salman, Samir Jabbour, Eve Simoneau, Saleh Al-Abbad, Murad Al-Jiffry, Goffredo Arena, Petr Kavan, Peter Metrakos

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: This study describes the management of patients with bilobar colorectal liver metastases (CRLM). Methods: A retrospective collection of data on all patients with CRLM who were considered for staged resection (n= 85) from January 2003 to January 2011 was performed. Patients who underwent one hepatic resection were considered to have had a failed staged resection (FSR), whereas those who underwent a second or third hepatic resection to produce a cure were considered to have had a successful staged resection (SSR). Survival was calculated from the date of diagnosis of liver metastases. Complete follow-up and dates of death were obtained from the Government of Quebec population database. Results: Median survival was 46 months (range: 30-62 months) in the SSR group and 22 months (range: 19-29 months) in the FSR group. Rates of 5-year survival were 42% and 4% in the SSR and FSR groups, respectively. Fifteen of the 19 patients who remained alive at the last follow-up date belonged to the SSR group. Conclusions: In patients in whom staged resection for bilobar CRLM is feasible, surgery would appear to offer benefit.

Original languageEnglish (US)
Pages (from-to)782-789
Number of pages8
JournalHPB
Volume14
Issue number11
DOIs
StatePublished - Nov 2012
Externally publishedYes

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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