Stage B adenocarcinoma of the prostate: Transrectal US and pathologic correlation of nonmalignant hypoechoic peripheral zone lesions

Ulrike M. Hamper, Sheila Sheth, Patrick C. Walsh, Patrice M. Holtz, Jonathan I. Epstein

Research output: Contribution to journalArticle

Abstract

Various benign conditions have been found to cause hypoechoic lesions in the prostate gland, thus mimicking the sonographic appearance of early prostatic cancer. Transrectal sonograms in a large series of patients with biopsy-proved clinical stage B prostatic cancer were retrospectively reviewed to determine the pathologic correlate to benign hypoechoic peripheral zone lesions. Transrectal sonograms demonstrated hypoechoic lesions that did not represent cancer in 25 of 160 patients examined. All lesions were contralateral to the carcinoma. Pathologic correlation was found in 24 of the 25 lesions. The results of this study show that contralateral hypoechoic lesions in patients with pathologically proved prostatic cancer do not necessarily imply bilateral tumor involvement; they accounted for benign lesions that mimicked the sonographic appearance of malignant tumors and thus produced a false-positive rate for cancer in the contralateral lobe of 16% of patients (25 of 160) with clinical stage B cancer.

Original languageEnglish (US)
Pages (from-to)101-104
Number of pages4
JournalRADIOLOGY
Volume180
Issue number1
DOIs
StatePublished - Jul 1991

Keywords

  • Prostate, US studies, 844.12989
  • Prostate, biopsy, 844.126
  • Prostate, dysplasia, 844.319
  • Prostate, neoplasms, 844.31, 844.32

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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