Stable intercellular bridges in development: The cytoskeleton lining the tunnel

Research output: Contribution to journalReview articlepeer-review

108 Scopus citations


A wide variety of intercellular junctions that are involved with cell adhesion or signal transduction have been described in recent years. A widespread but less well-characterized type of intercellular junction is the stable intercellular bridge. Several organisms use stable intercellular bridges as cytoplasmic connections, probably to allow rapid transfer of information and organelles between cells. Here, the authors take a detailed look at the assembly of intercellular bridges called ring canals in the Drosophila germline and discuss how examination of mutants that disrupt Drosophila ovarian ring canal assembly indicates that these bridges are required for intercellular transport of cytoplasm.

Original languageEnglish (US)
Pages (from-to)474-479
Number of pages6
JournalTrends in Cell Biology
Issue number12
StatePublished - Dec 1996
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology


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