Paleopathological evidence and descriptions of upper gastrointestinal bleeds (UGIB), i.e., proximal to the ligament of Treitz, are limited and sometimes inconclusive. The earliest potential reference to UGIB can be traced to the Ebers papyrus (circa 1550 BC) describing a blood-nest in a patient who acutely turned pale and later expired . A more conclusive familiarity of peptic ulcer pathology was noted by Roman scientists during the first century  and thus we know that UGIB have been known for at least 2000 years. Risk factors for UGIB were most likely omnipresent and, as such, suffering from UGIB has more than likely always plagued humans.
|Original language||English (US)|
|Title of host publication||Gastrointestinal Bleeding|
|Subtitle of host publication||A Practical Approach to Diagnosis and Management|
|Publisher||Springer New York|
|Number of pages||10|
|State||Published - 2010|
ASJC Scopus subject areas