Sporothrix schenckii lymphadentitis in a male with x-linked chronic granulomatous disease

Jessica R. Trotter; Panida Sriaroon; David Berman; Aleksandra Petrovic; Jennifer W. Leiding

doi:10.1007/s10875-013-9968-0

Sporothrix schenckii lymphadentitis in a male with x-linked chronic granulomatous disease

Jessica R. Trotter, Panida Sriaroon, David Berman, Aleksandra Petrovic, Jennifer W. Leiding

All Children's Hospital

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Sporothrix schenckii lymphadenitis was identified in a 33 month old male with X-linked chronic granulomatous disease (CGD). S. schenckii is a dimorphic catalase producing fungus found in the soil of temperate and tropical climates. Host defense against S. schenckii relies primarily on innate and cellular responses and gp91^phox-/- mice are susceptible to disseminated infection. This case represents the first report of susceptibility to sporotrichosis in a patient with CGD.

Original language	English (US)
Pages (from-to)	49-52
Number of pages	4
Journal	Journal of Clinical Immunology
Volume	34
Issue number	1
DOIs	https://doi.org/10.1007/s10875-013-9968-0
State	Published - Jan 2014

Keywords

Chronic granulomatous disease
Sporothrix schenckii
lymphadenitis
neck abscess
sporotrichosis

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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title = "Sporothrix schenckii lymphadentitis in a male with x-linked chronic granulomatous disease",

abstract = "Sporothrix schenckii lymphadenitis was identified in a 33 month old male with X-linked chronic granulomatous disease (CGD). S. schenckii is a dimorphic catalase producing fungus found in the soil of temperate and tropical climates. Host defense against S. schenckii relies primarily on innate and cellular responses and gp91phox-/- mice are susceptible to disseminated infection. This case represents the first report of susceptibility to sporotrichosis in a patient with CGD.",

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AU - Trotter, Jessica R.

AU - Sriaroon, Panida

AU - Berman, David

AU - Petrovic, Aleksandra

AU - Leiding, Jennifer W.

PY - 2014/1

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AB - Sporothrix schenckii lymphadenitis was identified in a 33 month old male with X-linked chronic granulomatous disease (CGD). S. schenckii is a dimorphic catalase producing fungus found in the soil of temperate and tropical climates. Host defense against S. schenckii relies primarily on innate and cellular responses and gp91phox-/- mice are susceptible to disseminated infection. This case represents the first report of susceptibility to sporotrichosis in a patient with CGD.

KW - Chronic granulomatous disease

KW - Sporothrix schenckii

KW - lymphadenitis

KW - neck abscess

KW - sporotrichosis

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Sporothrix schenckii lymphadentitis in a male with x-linked chronic granulomatous disease

Abstract

Keywords

ASJC Scopus subject areas

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