Sporothrix schenckii lymphadentitis in a male with x-linked chronic granulomatous disease

Jessica R. Trotter, Panida Sriaroon, David Berman, Aleksandra Petrovic, Jennifer W. Leiding

Research output: Contribution to journalArticlepeer-review

Abstract

Sporothrix schenckii lymphadenitis was identified in a 33 month old male with X-linked chronic granulomatous disease (CGD). S. schenckii is a dimorphic catalase producing fungus found in the soil of temperate and tropical climates. Host defense against S. schenckii relies primarily on innate and cellular responses and gp91phox-/- mice are susceptible to disseminated infection. This case represents the first report of susceptibility to sporotrichosis in a patient with CGD.

Original languageEnglish (US)
Pages (from-to)49-52
Number of pages4
JournalJournal of Clinical Immunology
Volume34
Issue number1
DOIs
StatePublished - Jan 2014
Externally publishedYes

Keywords

  • Chronic granulomatous disease
  • Sporothrix schenckii
  • lymphadenitis
  • neck abscess
  • sporotrichosis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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