Sporadic non-a, non-b hepatitis: Frequency and epidemiology in an urban u.s. population

R. E. Sampliner, M. J. Alter, R. J. Gerety, L. A. Smallwood, E. Tabor, F. Deinhardt, G. Frosner, G. M. Matanoski

Research output: Contribution to journalArticlepeer-review

206 Scopus citations

Abstract

Patients with acute viral hepatitis were identified at five hospitals in Baltimore, Maryland between February 1979-August 1980. Of the 295 patients with serologically diagnosed hepatitis, 42070 had non-A, non-B hepatitis; 48% had hepatitis B; and 10% had hepatitis A. Compared with matched control patients with no liver disease, patients with non-A, non-B hepatitis more often had received a blood transfusion (11 % vs. 0, P < 0.001), used parenteral drugs (42% vs. 4%, P < 0.001), were employed as health workers in direct patient care or hospital laboratory work (6% vs. 3%, P < 0.05), had personal contact with others who had hepatitis (16% vs. 1 %, P < 0.001), or had ingested raw shellfish (34% vs. 20%, P < 0.01). A history of previous clinical hepatitis and serologic markers indicating previous hepatitis B infection were found in patients with non-A, non-B hepatitis more often than in the control patients. Chronic non-A, non-B hepatitis was found in 34 (42.5%) of 80 patients with non-A, non-B hepatitis.

Original languageEnglish (US)
Pages (from-to)886-893
Number of pages8
JournalJournal of Infectious Diseases
Volume145
Issue number6
DOIs
StatePublished - Jun 1982

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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