TY - JOUR
T1 - Sporadic non-a, non-b hepatitis
T2 - Frequency and epidemiology in an urban u.s. population
AU - Sampliner, R. E.
AU - Alter, M. J.
AU - Gerety, R. J.
AU - Smallwood, L. A.
AU - Tabor, E.
AU - Deinhardt, F.
AU - Frosner, G.
AU - Matanoski, G. M.
N1 - Funding Information:
Received for publication October 15, 1981, and in revised form January 18, 1982. This work was supported in part by contract no. 223-79-1011 from the Food and Drug Administration and by grant no. 5MOI RROO722-07 from the National Institutes of Health. We thank Dr. Neal Nathanson, Dr. Timothy Townsend, Dr. Earl Diamond, Ilene Bloom, Tina Marrelli-Klein, Roberta Truitt, Dr. Martha Linet, Paul Bailey, A. J. Shawver, D. Gilbert, L. Stevan, Dr. N. Pollok, and the staffs of The Johns Hopkins, University of Maryland, Baltimore City, Loch Raven V.A., and Maryland General Hospitals. Please address requests for reprints to Dr. M. J. Alter at her present address: Hepatitis and Viral Enteritis Division, Centers for Disease Control, 4402 North Seventh Street, Phoenix, Arizona 85014. ... Present address: V.A. Medical Center, University of Arizona Health Sciences Center, Tucson, Arizona.
PY - 1982/6
Y1 - 1982/6
N2 - Patients with acute viral hepatitis were identified at five hospitals in Baltimore, Maryland between February 1979-August 1980. Of the 295 patients with serologically diagnosed hepatitis, 42070 had non-A, non-B hepatitis; 48% had hepatitis B; and 10% had hepatitis A. Compared with matched control patients with no liver disease, patients with non-A, non-B hepatitis more often had received a blood transfusion (11 % vs. 0, P < 0.001), used parenteral drugs (42% vs. 4%, P < 0.001), were employed as health workers in direct patient care or hospital laboratory work (6% vs. 3%, P < 0.05), had personal contact with others who had hepatitis (16% vs. 1 %, P < 0.001), or had ingested raw shellfish (34% vs. 20%, P < 0.01). A history of previous clinical hepatitis and serologic markers indicating previous hepatitis B infection were found in patients with non-A, non-B hepatitis more often than in the control patients. Chronic non-A, non-B hepatitis was found in 34 (42.5%) of 80 patients with non-A, non-B hepatitis.
AB - Patients with acute viral hepatitis were identified at five hospitals in Baltimore, Maryland between February 1979-August 1980. Of the 295 patients with serologically diagnosed hepatitis, 42070 had non-A, non-B hepatitis; 48% had hepatitis B; and 10% had hepatitis A. Compared with matched control patients with no liver disease, patients with non-A, non-B hepatitis more often had received a blood transfusion (11 % vs. 0, P < 0.001), used parenteral drugs (42% vs. 4%, P < 0.001), were employed as health workers in direct patient care or hospital laboratory work (6% vs. 3%, P < 0.05), had personal contact with others who had hepatitis (16% vs. 1 %, P < 0.001), or had ingested raw shellfish (34% vs. 20%, P < 0.01). A history of previous clinical hepatitis and serologic markers indicating previous hepatitis B infection were found in patients with non-A, non-B hepatitis more often than in the control patients. Chronic non-A, non-B hepatitis was found in 34 (42.5%) of 80 patients with non-A, non-B hepatitis.
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U2 - 10.1093/infdis/145.6.886
DO - 10.1093/infdis/145.6.886
M3 - Article
C2 - 6806403
AN - SCOPUS:0019948091
SN - 0022-1899
VL - 145
SP - 886
EP - 893
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
IS - 6
ER -