Spontaneous remission in patients with essential biepharospasm and Meige syndrome

Anthony Castelbuono, Neil R. Miller

Research output: Contribution to journalArticlepeer-review


PURPOSE: To determine the frequency of remission in patients with essential blepharospasm and Meige syndrome. METHOD: Retrospective analysis of patients by means of questionnaire in an institutional setting. RESULTS: Among 238 patients diagnosed in a single institution as having essential blepharospasm or Meige syndrome, 27 (11.3%) claimed to be symptom free without curative surgery. The average time between onset and resolution in the patients who claimed remission was 4.85 years (range, 3 months to 22 years). Among these patients, the duration of remission averaged 6.33 years (range, 1 year to 14 years). CONCLUSION: Patients with essential blepharospasm or Meige syndrome have a small but definite potential for spontaneous remission of symptoms, particularly within the first 5 years after onset of symptoms.

Original languageEnglish (US)
Pages (from-to)432-435
Number of pages4
JournalAmerican journal of ophthalmology
Issue number3
StatePublished - Sep 1 1998

ASJC Scopus subject areas

  • Ophthalmology

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