Spontaneous regression (autoinfarction) of proliferative sickle retinopathy

Krishan C. Nagpal, Dimitrios Patrianakos, George K. Asdourian, Morton F Goldberg, Maurice Rabb, Lee Jam Pol

Research output: Contribution to journalArticle

Abstract

Of 45 patients with proliferative sickle retinopathy in stages III, IV, and V, nine patients (eight with hemoglobin SC disease, one with sickle cell thalassemia) showed spontaneous regression (autoinfarction) of retinal sea fans. One mechanism involved in autoinfarction of neovascular tissue is progressive, centripetal retraction of the anterior vascular arcade of the peripheral retina. In addition, vitreous traction on feeder vessels may result in sluggish blood flow and occlusion of these vessels, or may tear the sea fan completely away from its feeder vessels. In view of the many incidences of vitreous hemorrhages that occur in patients with proliferative retinopathy, however, we recommend treatment of neovascularization rather than prolonged observation.

Original languageEnglish (US)
Pages (from-to)885-892
Number of pages8
JournalAmerican Journal of Ophthalmology
Volume80
Issue number5
StatePublished - 1975
Externally publishedYes

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Oceans and Seas
Hemoglobin SC Disease
Vitreous Hemorrhage
Thalassemia
Traction
Tears
Blood Vessels
Retina
Observation
Incidence
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Nagpal, K. C., Patrianakos, D., Asdourian, G. K., Goldberg, M. F., Rabb, M., & Pol, L. J. (1975). Spontaneous regression (autoinfarction) of proliferative sickle retinopathy. American Journal of Ophthalmology, 80(5), 885-892.

Spontaneous regression (autoinfarction) of proliferative sickle retinopathy. / Nagpal, Krishan C.; Patrianakos, Dimitrios; Asdourian, George K.; Goldberg, Morton F; Rabb, Maurice; Pol, Lee Jam.

In: American Journal of Ophthalmology, Vol. 80, No. 5, 1975, p. 885-892.

Research output: Contribution to journalArticle

Nagpal, KC, Patrianakos, D, Asdourian, GK, Goldberg, MF, Rabb, M & Pol, LJ 1975, 'Spontaneous regression (autoinfarction) of proliferative sickle retinopathy', American Journal of Ophthalmology, vol. 80, no. 5, pp. 885-892.
Nagpal, Krishan C. ; Patrianakos, Dimitrios ; Asdourian, George K. ; Goldberg, Morton F ; Rabb, Maurice ; Pol, Lee Jam. / Spontaneous regression (autoinfarction) of proliferative sickle retinopathy. In: American Journal of Ophthalmology. 1975 ; Vol. 80, No. 5. pp. 885-892.
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