TY - JOUR
T1 - Spindle-cell variant of primary cutaneous follicle center lymphoma spreading to the hepatobiliary tree, mimicking Klatskin tumor
AU - Rozati, Sima
AU - Kerl, Katrin
AU - Kempf, Werner
AU - Tinguely, Marianne
AU - Zimmermann, Dieter R.
AU - Dummer, Reinhard
AU - Cozzio, Antonio
PY - 2013/1/1
Y1 - 2013/1/1
N2 - Primary cutaneous follicle center lymphoma (pcFCL) is an indolent type of primary cutaneous B-cell lymphoma (pcBCL) rarely disseminating to other organs. PcBCL with spindle-cell morphology has been described as a rare variant of pcFCL but the prognosis data of this variant is sparse. We report a rare case of spindle-cell pcFCL with CD20+, CD79a+, CD3+, Bcl-6+, Mum-1- and CD10-tumor cells that infiltrated the hepatic hilum, mimicking a Klatskin tumor. On the basis of the sparse published data on spindle-cell morphology of pcBCL, this growth pattern should elicit awareness of an increased risk of systemic involvement in the otherwise indolent pcFCL.
AB - Primary cutaneous follicle center lymphoma (pcFCL) is an indolent type of primary cutaneous B-cell lymphoma (pcBCL) rarely disseminating to other organs. PcBCL with spindle-cell morphology has been described as a rare variant of pcFCL but the prognosis data of this variant is sparse. We report a rare case of spindle-cell pcFCL with CD20+, CD79a+, CD3+, Bcl-6+, Mum-1- and CD10-tumor cells that infiltrated the hepatic hilum, mimicking a Klatskin tumor. On the basis of the sparse published data on spindle-cell morphology of pcBCL, this growth pattern should elicit awareness of an increased risk of systemic involvement in the otherwise indolent pcFCL.
KW - Klatskin mimicking tumor
KW - cutaneous B-cell lymphoma
KW - cutaneous spindle-cell lymphoma
KW - hilar cholangiocarcinoma
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U2 - 10.1111/cup.12017
DO - 10.1111/cup.12017
M3 - Article
C2 - 23167279
AN - SCOPUS:84872876156
VL - 40
SP - 56
EP - 60
JO - Journal of Cutaneous Pathology
JF - Journal of Cutaneous Pathology
SN - 0303-6987
IS - 1
ER -