TY - JOUR
T1 - Spinal metastasis as the initial manifestation of a nonsecretory glucagonoma
AU - Aggarwal, Anjana
AU - Brainard, Jennifer
AU - Brotman, Daniel J.
PY - 2003/2/1
Y1 - 2003/2/1
N2 - Glucagonomas are rare functional endocrine tumors of the pancreas that classically present with symptoms of glucagon excess, including rash, hyperglycemia, diarrhea, and weight loss. Metastatic disease at presentation is common but is often limited to the liver and regional lymph nodes. We describe an unusual case of a patient with glucagonoma who presented with a pathologic vertebral fracture. This tumor had no evidence of active hormone secretion but tested positive for glucagon by immunohistochemical staining.
AB - Glucagonomas are rare functional endocrine tumors of the pancreas that classically present with symptoms of glucagon excess, including rash, hyperglycemia, diarrhea, and weight loss. Metastatic disease at presentation is common but is often limited to the liver and regional lymph nodes. We describe an unusual case of a patient with glucagonoma who presented with a pathologic vertebral fracture. This tumor had no evidence of active hormone secretion but tested positive for glucagon by immunohistochemical staining.
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U2 - 10.1097/01.SMJ.0000051272.02055.A6
DO - 10.1097/01.SMJ.0000051272.02055.A6
M3 - Article
C2 - 12630646
AN - SCOPUS:0037328453
SN - 0038-4348
VL - 96
SP - 190
EP - 193
JO - Southern medical journal
JF - Southern medical journal
IS - 2
ER -