Spinal drug delivery

Theodore S. Grabow; David Derdzinski; Peter S. Staats

doi:10.1007/s11916-001-0068-0

Spinal drug delivery

Theodore S. Grabow, David Derdzinski, Peter S. Staats

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Clinicians currently base decisions regarding the use of intrathecal drug therapy for chronic pain on reports from uncontrolled and retrospective studies that fail to rely on standardized outcome measures. In this article, we summarize what is known about currently administered intrathecal therapies, including opioids, gamma-aminobutyric acid agonists, alpha-2 adrenoreceptor agonists, local anesthetics (sodium channel antagonists), calcium channel antagonists, miscellaneous agents, and drug combination therapy. In addition, we offer a brief look at novel approaches that may revolutionize intrathecal drug delivery.

Original language	English (US)
Pages (from-to)	510-516
Number of pages	7
Journal	Current pain and headache reports
Volume	5
Issue number	6
DOIs	https://doi.org/10.1007/s11916-001-0068-0
State	Published - Dec 2001
Externally published	Yes

Keywords

Baclofen
Bupivacaine
Cancer Pain
Morphine
Neuropathic Pain

ASJC Scopus subject areas

Clinical Neurology
Anesthesiology and Pain Medicine

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10.1007/s11916-001-0068-0

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title = "Spinal drug delivery",

abstract = "Clinicians currently base decisions regarding the use of intrathecal drug therapy for chronic pain on reports from uncontrolled and retrospective studies that fail to rely on standardized outcome measures. In this article, we summarize what is known about currently administered intrathecal therapies, including opioids, gamma-aminobutyric acid agonists, alpha-2 adrenoreceptor agonists, local anesthetics (sodium channel antagonists), calcium channel antagonists, miscellaneous agents, and drug combination therapy. In addition, we offer a brief look at novel approaches that may revolutionize intrathecal drug delivery.",

keywords = "Baclofen, Bupivacaine, Cancer Pain, Morphine, Neuropathic Pain",

author = "Grabow, {Theodore S.} and David Derdzinski and Staats, {Peter S.}",

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AU - Grabow, Theodore S.

AU - Derdzinski, David

AU - Staats, Peter S.

PY - 2001/12

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AB - Clinicians currently base decisions regarding the use of intrathecal drug therapy for chronic pain on reports from uncontrolled and retrospective studies that fail to rely on standardized outcome measures. In this article, we summarize what is known about currently administered intrathecal therapies, including opioids, gamma-aminobutyric acid agonists, alpha-2 adrenoreceptor agonists, local anesthetics (sodium channel antagonists), calcium channel antagonists, miscellaneous agents, and drug combination therapy. In addition, we offer a brief look at novel approaches that may revolutionize intrathecal drug delivery.

KW - Baclofen

KW - Bupivacaine

KW - Cancer Pain

KW - Morphine

KW - Neuropathic Pain

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JO - Current pain and headache reports

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ER -

Spinal drug delivery

Abstract

Keywords

ASJC Scopus subject areas

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