Sphenoid sinus expansion: A radiographic sign of intracranial hypotension and the sunken eyes, sagging brain syndrome

Research output: Contribution to journalArticle

Abstract

Purpose: To test the hypothesis that in patient with sunken eyes, sagging brain syndrome, bone remodeling is not limited to the orbits. Volumetric analysis of the sphenoid sinus is performed in this study. Methods: In this university-based retrospective case-control study, the dimensions of the sphenoid sinus were measured in four patients (2 males, 2 females; mean age 26.3 years, range 16-38 years) out of five individuals identified with sunken eyes, sagging brain syndrome. Three measurements were taken: the distance between the orbital apices, the posterior extension of the sphenoid sinus posterior to the orbital apices, and the maximal horizontal width. The mean of each was determined and compared to that of the control group (5 males, 5 females; mean age 35.6 years, range 23-45 years). Results: Posterior extension and width of the sphenoid sinus were markedly larger in the enophthalmic patients than in the control group: posterior extension (26.3±4.1 mm vs 13.4±6.3 mm, P=.0015, Student's t test), width (39.2±8.7 mm vs 25.1±6.9 mm, P=.0035, Student's t test). Mean distance between the orbital apices was slightly greater (36.3±1.7 mm vs 34.1±2.1 mm, P=.047, Student's t test). Conclusions: Skull remodeling occurring in association with intracranial hypotension after ventriculoperitoneal shunting is not limited to the orbits. In this study we have demonstrated expansion of the sphenoid sinus. This finding adds to our knowledge and understanding of the scope of the sunken eyes, sagging brain syndrome and elucidates a clinically useful radiographic sign.

Original languageEnglish (US)
Pages (from-to)145-154
Number of pages10
JournalTransactions of the American Ophthalmological Society
Volume111
StatePublished - 2013

Fingerprint

Intracranial Hypotension
Sphenoid Sinus
Brain
Orbit
Students
Control Groups
Bone Remodeling
Skull
Case-Control Studies

ASJC Scopus subject areas

  • Ophthalmology

Cite this

@article{762cbd69a8da4bedb345e989cc299058,
title = "Sphenoid sinus expansion: A radiographic sign of intracranial hypotension and the sunken eyes, sagging brain syndrome",
abstract = "Purpose: To test the hypothesis that in patient with sunken eyes, sagging brain syndrome, bone remodeling is not limited to the orbits. Volumetric analysis of the sphenoid sinus is performed in this study. Methods: In this university-based retrospective case-control study, the dimensions of the sphenoid sinus were measured in four patients (2 males, 2 females; mean age 26.3 years, range 16-38 years) out of five individuals identified with sunken eyes, sagging brain syndrome. Three measurements were taken: the distance between the orbital apices, the posterior extension of the sphenoid sinus posterior to the orbital apices, and the maximal horizontal width. The mean of each was determined and compared to that of the control group (5 males, 5 females; mean age 35.6 years, range 23-45 years). Results: Posterior extension and width of the sphenoid sinus were markedly larger in the enophthalmic patients than in the control group: posterior extension (26.3±4.1 mm vs 13.4±6.3 mm, P=.0015, Student's t test), width (39.2±8.7 mm vs 25.1±6.9 mm, P=.0035, Student's t test). Mean distance between the orbital apices was slightly greater (36.3±1.7 mm vs 34.1±2.1 mm, P=.047, Student's t test). Conclusions: Skull remodeling occurring in association with intracranial hypotension after ventriculoperitoneal shunting is not limited to the orbits. In this study we have demonstrated expansion of the sphenoid sinus. This finding adds to our knowledge and understanding of the scope of the sunken eyes, sagging brain syndrome and elucidates a clinically useful radiographic sign.",
author = "McCulley, {Timothy J}",
year = "2013",
language = "English (US)",
volume = "111",
pages = "145--154",
journal = "Transactions of the American Ophthalmological Society",
issn = "0065-9533",
publisher = "American Ophthalmological Society",

}

TY - JOUR

T1 - Sphenoid sinus expansion

T2 - A radiographic sign of intracranial hypotension and the sunken eyes, sagging brain syndrome

AU - McCulley, Timothy J

PY - 2013

Y1 - 2013

N2 - Purpose: To test the hypothesis that in patient with sunken eyes, sagging brain syndrome, bone remodeling is not limited to the orbits. Volumetric analysis of the sphenoid sinus is performed in this study. Methods: In this university-based retrospective case-control study, the dimensions of the sphenoid sinus were measured in four patients (2 males, 2 females; mean age 26.3 years, range 16-38 years) out of five individuals identified with sunken eyes, sagging brain syndrome. Three measurements were taken: the distance between the orbital apices, the posterior extension of the sphenoid sinus posterior to the orbital apices, and the maximal horizontal width. The mean of each was determined and compared to that of the control group (5 males, 5 females; mean age 35.6 years, range 23-45 years). Results: Posterior extension and width of the sphenoid sinus were markedly larger in the enophthalmic patients than in the control group: posterior extension (26.3±4.1 mm vs 13.4±6.3 mm, P=.0015, Student's t test), width (39.2±8.7 mm vs 25.1±6.9 mm, P=.0035, Student's t test). Mean distance between the orbital apices was slightly greater (36.3±1.7 mm vs 34.1±2.1 mm, P=.047, Student's t test). Conclusions: Skull remodeling occurring in association with intracranial hypotension after ventriculoperitoneal shunting is not limited to the orbits. In this study we have demonstrated expansion of the sphenoid sinus. This finding adds to our knowledge and understanding of the scope of the sunken eyes, sagging brain syndrome and elucidates a clinically useful radiographic sign.

AB - Purpose: To test the hypothesis that in patient with sunken eyes, sagging brain syndrome, bone remodeling is not limited to the orbits. Volumetric analysis of the sphenoid sinus is performed in this study. Methods: In this university-based retrospective case-control study, the dimensions of the sphenoid sinus were measured in four patients (2 males, 2 females; mean age 26.3 years, range 16-38 years) out of five individuals identified with sunken eyes, sagging brain syndrome. Three measurements were taken: the distance between the orbital apices, the posterior extension of the sphenoid sinus posterior to the orbital apices, and the maximal horizontal width. The mean of each was determined and compared to that of the control group (5 males, 5 females; mean age 35.6 years, range 23-45 years). Results: Posterior extension and width of the sphenoid sinus were markedly larger in the enophthalmic patients than in the control group: posterior extension (26.3±4.1 mm vs 13.4±6.3 mm, P=.0015, Student's t test), width (39.2±8.7 mm vs 25.1±6.9 mm, P=.0035, Student's t test). Mean distance between the orbital apices was slightly greater (36.3±1.7 mm vs 34.1±2.1 mm, P=.047, Student's t test). Conclusions: Skull remodeling occurring in association with intracranial hypotension after ventriculoperitoneal shunting is not limited to the orbits. In this study we have demonstrated expansion of the sphenoid sinus. This finding adds to our knowledge and understanding of the scope of the sunken eyes, sagging brain syndrome and elucidates a clinically useful radiographic sign.

UR - http://www.scopus.com/inward/record.url?scp=84885793830&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84885793830&partnerID=8YFLogxK

M3 - Article

C2 - 24167328

AN - SCOPUS:84885793830

VL - 111

SP - 145

EP - 154

JO - Transactions of the American Ophthalmological Society

JF - Transactions of the American Ophthalmological Society

SN - 0065-9533

ER -